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Davies, Michael, Jones, Rhys DO, Grime, Ken, Jansson-Lofmark, Rasmus, Fretland, Adrian J, Winiwarter, Susanne, Morgan, Paul and McGinnity, Dermot F
(2020)
Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades.
TRENDS IN PHARMACOLOGICAL SCIENCES, 41 (6).
pp. 390-408.
Foster, Alison J, Chouhan, Bhavik, Regan, Sophie L, Rollison, Helen, Amberntsson, Sara, Andersson, Linda C, Srivastava, Abhishek, Darnell, Malin, Cairns, Jonathan, Lazic, Stanley E et al (show 8 more authors)
(2019)
Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.
ARCHIVES OF TOXICOLOGY, 93 (4).
pp. 1021-1037.
Weaver, Richard J, Blomme, Eric A, Chadwick, Amy E ORCID: 0000-0002-7399-8655, Copple, Ian M ORCID: 0000-0003-4101-1913, Gerets, Helga HJ, Goldring, Christopher E, Guillouzo, Andre, Hewitt, Philip G, Ingelman-Sundberg, Magnus, Jensen, Klaus Gjervig et al (show 12 more authors)
(2020)
Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models.
NATURE REVIEWS DRUG DISCOVERY, 19 (2).
pp. 131-148.