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Number of items: 14.


Ranganath, Lakshminarayan R ORCID: 0000-0002-4205-2269, Milan, Anna M, Hughes, Andrew T, Khedr, Milad, Norman, Brendan P ORCID: 0000-0001-9293-4852, Alsbou, Mohammed, Imrich, Richard, Gornall, Matthew, Sireau, Nicolas, Gallagher, James A
et al (show 1 more authors) (2022) Comparing nitisinone 2 mg and 10 mg in the treatment of alkaptonuria-An approach using statistical modelling. JIMD reports, 63 (1). 80 - 92.


Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Ross, Gordon A, Milan, Anna M ORCID: 0000-0002-0452-2338, Hughes, Andrew T, Sutherland, Hazel, Jarvis, Jonathan C, Roberts, Norman B, Gallagher, James A ORCID: 0000-0002-0852-279X and Ranganath, Lakshminarayan R
(2019) A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria. Clinical chemistry.


Hughes, Juliette H ORCID: 0000-0001-6155-4136, Liu, Ke, Plagge, Antonius ORCID: 0000-0001-6592-1343, Wilson, Peter JM, Sutherland, Hazel, Norman, Brendan P ORCID: 0000-0001-9293-4852, Hughes, Andrew T, Keenan, Craig M ORCID: 0000-0002-8782-8016, Milan, Anna M ORCID: 0000-0002-0452-2338, Sakai, Takao ORCID: 0000-0002-7375-5450
et al (show 3 more authors) (2019) Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria. Human Molecular Genetics, 28 (23). 3928 - 3939.


Hughes, Juliette H ORCID: 0000-0001-6155-4136, Liu, Ke, Plagge, Antonius ORCID: 0000-0001-6592-1343, Wilson, Peter JM, Sutherland, Hazel, Norman, Brendan P, Hughes, Andrew T, Keenan, Craig M, Milan, Anna M, Sakai, Takao ORCID: 0000-0002-7375-5450
et al (show 3 more authors) (2019) Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria. Human molecular genetics.


Ranganath, Lakshminarayan R, Psarelli, Eftychia Eirini ORCID: 0000-0002-3102-0288, Arnoux, Jean-Baptiste, Braconi, Daniela, Briggs, Michael, Broijersen, Anders, Loftus, Nadia, Bygott, Helen, Cox, Trevor F, Davison, Andrew S ORCID: 0000-0001-5501-4475
et al (show 39 more authors) (2020) Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial. The Lancet Diabetes and Endocrinology, 8 (9). 762 - 772.


Davison, Andrew S, Norman, Brendan P, Ross, Gordon A, Hughes, Andrew T, Khedr, Milad ORCID: 0000-0002-4998-2397, Milan, Anna M, Gallagher, James A and Ranganath, Lakshminarayan R
(2019) Evaluation of the serum metabolome of patients with alkaptonuria before and after two years of treatment with nitisinone using LC-QTOF-MS. JIMD reports, 48 (1). 67 - 74.


Ranganath, Lakshminarayan R, Milan, Anna M ORCID: 0000-0002-0452-2338, Hughes, Andrew T, Khedr, Milad ORCID: 0000-0002-4998-2397, Davison, Andrew S ORCID: 0000-0001-5501-4475, Shweihdi, Ella, Norman, Brendan P ORCID: 0000-0001-9293-4852, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Bygott, Helen, Luangrath, Emily
et al (show 20 more authors) (2020) Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 43 (4). 737 - 747.


Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Sutherland, Hazel, Wilson, Peter JM, Berry, Neil G ORCID: 0000-0003-1928-0738, Hughes, Andrew T, Milan, Anna M, Jarvis, Jonathan C, Roberts, Norman B
et al (show 3 more authors) (2022) Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism. GENES & DISEASES, 9 (4). 1129 - 1142.


Khedr, Milad ORCID: 0000-0002-4998-2397, Cooper, Maggie S, Hughes, Andrew T, Milan, Anna M ORCID: 0000-0002-0452-2338, Davison, Andrew S ORCID: 0000-0001-5501-4475, Norman, Brendan P ORCID: 0000-0001-9293-4852, Sutherland, Hazel, Jarvis, Jonathan C, Fitzgerald, Richard, Markinson, Louise
et al (show 5 more authors) (2020) Nitisinone causes acquired tyrosinosis in alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 43 (5). 1014 - 1023.


Ranganath, Lakshminarayan R, Norman, Brendan P ORCID: 0000-0001-9293-4852 and Gallagher, James A
(2019) Ochronotic pigmentation is caused by homogentisic acid and is the key event in alkaptonuria leading to the destructive consequences of the disease-A review. JOURNAL OF INHERITED METABOLIC DISEASE, 42 (5). 776 - 792.


Chow, Wing Ying, Norman, Brendan P ORCID: 0000-0001-9293-4852, Roberts, Norman B, Ranganath, Lakshminarayan R, Teutloff, Christian, Bittl, Robert, Duer, Melinda J, Gallagher, James A ORCID: 0000-0002-0852-279X and Oschkinat, Hartmut
(2020) Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 59 (29). 11937 - 11942.


Chow, Wing Ying ORCID: 0000-0003-0719-5958, Norman, Brendan P, Roberts, Norman B, Ranganath, Lakshminarayan R ORCID: 0000-0002-4205-2269, Teutloff, Christian ORCID: 0000-0001-6949-1985, Bittl, Robert ORCID: 0000-0003-4103-3768, Duer, Melinda J ORCID: 0000-0002-9196-5072, Gallagher, James A and Oschkinat, Hartmut ORCID: 0000-0002-4384-9544
(2020) Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose. Angewandte Chemie, 132 (29). 12035 - 12040.


Loh, Hui-Yi, Norman, Brendan P ORCID: 0000-0001-9293-4852, Lai, Kok-Song, Abd Rahman, Nik Mohd Afizan Nik, Alitheen, Noorjahan Banu Mohamed and Osman, Mohd Azuraidi
(2019) The Regulatory Role of MicroRNAs in Breast Cancer. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20 (19).


Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Sutherland, Hazel, Wilson, Peter J, Berry, Neil G, Hughes, Andrew T, Milan, Anna M, Jarvis, Jonathan C, Roberts, Norman B
et al (show 3 more authors) Studies in alkaptonuria reveal new roles beyond drug clearance for phase I and II biotransformations in tyrosine metabolism. biorxiv. (Unpublished)

This list was generated on Sat Jul 30 11:51:28 2022 BST.