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Sharif, Umar, Mahmud, Nur Musfirah, Kay, Paul, Yang, Yit C, Harding, Simon P ORCID: 0000-0003-4676-1158, Grierson, Ian, Kamalden, Tengku Ain, Jackson, Malcolm J ORCID: 0000-0003-3683-8297 and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2019) Advanced glycation end products-related modulation of cathepsin L and NF-kappa B signalling effectors in retinal pigment epithelium lead to augmented response to TNF alpha. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 23 (1). 405 - 416.

Sharif, Umar, Mahmud, Nur Musfirah, Kay, Paul, Yang, Yit C, Harding, Simon ORCID: 0000-0003-4676-1158, Grierson, Ian, Kamalden, Tengku Ain, Jackson, Malcolm J ORCID: 0000-0003-3683-8297 and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2019) Advanced glycation end products‐related modulation of cathepsin L and NF‐κB signalling effectors in retinal pigment epithelium lead to augmented response to TNFα. Journal of Cellular and Molecular Medicine, 23 (1). pp. 405-416.

Kay, Paul, Yang, Yit C, Hiscott, Paul ORCID: 0000-0002-4273-2387, Gray, Donna, Maminishkis, Arvydas and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2014) Age-Related Changes of Cystatin C Expression and Polarized Secretion by Retinal Pigment Epithelium: Potential Age-Related Macular Degeneration Links. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 55 (2). pp. 926-934.

Sant'Anna, Ricardo, Navarro, Susanna, Ventura, Salvador, Paraoan, Luminita ORCID: 0000-0001-7568-7116 and Foguel, Debora (2016) Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration. FEBS LETTERS, 590 (5). pp. 644-654.

Carlsson, Emil, Sharif, Umar, Supharattanasitthi, Wasu and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2023) Analysis of Wild Type and Variant B Cystatin C Interactome in Retinal Pigment Epithelium Cells Reveals Variant B Interacting Mitochondrial Proteins. CELLS, 12 (5). 713-.

Duffy, Sean (2021) Analysis of region-specific DNA methylation changes in age-related macular degeneration: evaluating a role for the major risk factor smoking, and folate metabolism genes. Master of Philosophy thesis, University of Liverpool.

Supharattanasitthi, Wasu, Carlsson, Emil, Sharif, Umar and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2019) CRISPR/Cas9-mediated one step bi-allelic change of genomic DNA in iPSCs and human RPE cells <i>in vitro</i> with dual antibiotic selection. SCIENTIFIC REPORTS, 9 (1). 174-.

Awais, Raheela, Davies, Lyndsay and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2015) Characterizing the role of the p53 effector PERP in cell migration: Insights from uveal melanoma cells. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56 (7).

Muangnoi, Chawanphat, Bhuket, Pahweenvaj Ratnatilaka Na, Jithavech, Ponsiree, Supasena, Wiwat, Paraoan, Luminita ORCID: 0000-0001-7568-7116, Patumraj, Suthiluk and Rojsitthisake, Pornchai (2019) Curcumin diethyl disuccinate, a prodrug of curcumin, enhances anti-proliferative effect of curcumin against HepG2 cells via apoptosis induction. SCIENTIFIC REPORTS, 9 (1). 11718-.

Kay, Paul, Yang, Yit C and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2013) Directional protein secretion by the retinal pigment epithelium: roles in retinal health and the development of age-related macular degeneration. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 17 (7). pp. 833-843.

McDonnell, Samantha J, Spiller, David G, White, Michael RH, Prior, Ian A ORCID: 0000-0002-4055-5161 and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2019) ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions. CELL DEATH DISCOVERY, 5 (1). 132-.

McDonnell, Samantha, Spiller, David ORCID: 0000-0003-2502-6787, White, Michael, Prior, Ian ORCID: 0000-0002-4055-5161 and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2019) ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions.

Saptarshi, Neil, Green, Daniel, Cree, Angela, Lotery, Andrew, Paraoan, Luminita ORCID: 0000-0001-7568-7116 and Porter, Louise F ORCID: 0000-0002-7406-0319 (2021) Epigenetic Age Acceleration Is Not Associated with Age-Related Macular Degeneration. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (24). 13457-.

Suwanmanee, Gunticha, Tantrawatpan, Chairat, Kheolamai, Pakpoom, Paraoan, Luminita ORCID: 0000-0001-7568-7116 and Manochantr, Sirikul (2023) Fucoxanthin diminishes oxidative stress damage in human placenta-derived mesenchymal stem cells through the PI3K/Akt/Nrf-2 pathway. Scientific reports, 13 (1). p. 22974.

Jantalika, Tanachapa, Manochantr, Sirikul, Kheolamai, Pakpoom, Tantikanlayaporn, Duangrat, Saijuntha, Weerachai, Pinlaor, Somchai, Chairoungdua, Arthit, Paraoan, Luminita ORCID: 0000-0001-7568-7116 and Tantrawatpan, Chairat (2022) Human chorion-derived mesenchymal stem cells suppress JAK2/STAT3 signaling and induce apoptosis of cholangiocarcinoma cell lines. SCIENTIFIC REPORTS, 12 (1). 11341-.

Carlsson, Emil, Supharattanasitthi, Wasu, Jackson, Malcolm ORCID: 0000-0003-3683-8297 and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2020) Increased Rate of Retinal Pigment Epithelial Cell Migration and Pro-Angiogenic Potential Ensuing From Reduced Cystatin C Expression. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 61 (2). 9-.

Dhirachaikulpanich, Dhanach ORCID: 0000-0003-2234-1837, Li, Xin, Porter, Louise F ORCID: 0000-0002-7406-0319 and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2020) Integrated Microarray and RNAseq Transcriptomic Analysis of Retinal Pigment Epithelium/Choroid in Age-Related Macular Degeneration. Frontiers in Cell and Developmental Biology, 8. 808-.

Dhirachaikulpanich, Dhanach ORCID: 0000-0003-2234-1837, Lagger, Cyril ORCID: 0000-0003-1701-6896, Chatsirisupachai, Kasit, de Magalhaes, Joao Pedro ORCID: 0000-0002-6363-2465 and Paraoan, Luminita (2022) Intercellular communication analysis of the human retinal pigment epithelial and choroidal cells predicts pathways associated with aging, cellular senescence and age-related macular degeneration. FRONTIERS IN AGING NEUROSCIENCE, 14. 1016293-.

Saptarshi, Neil (2023) Investigating the Epigenetic Basis of Age- related Macular Degeneration: From Differentially Methylated Locus to Functional Consequence. PhD thesis, University of Liverpool.

Supharattanasitthi, W (2018) Investigation of the molecular signature of the ageing retinal pigment epithelium. PhD thesis, University of Liverpool.

Saptarshi, Neil, Porter, Louise F and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2022) PERK/EIF2AK3 integrates endoplasmic reticulum stress-induced apoptosis, oxidative stress and autophagy responses in immortalised retinal pigment epithelial cells. SCIENTIFIC REPORTS, 12 (1). 13324-.

Roberts, Owain and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2020) PERP-ing into diverse mechanisms of cancer pathogenesis: Regulation and role of the p53/p63 effector PERP. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 1874 (1). 188393-.

Muangnoi, Chawanphat, Phumsuay, Rianthong, Jongjitphisut, Nattapong, Waikasikorn, Pasin, Sangsawat, Monsin, Rashatasakhon, Paitoon, Paraoan, Luminita ORCID: 0000-0001-7568-7116 and Rojsitthisak, Pornchai (2021) Protective Effects of a Lutein Ester Prodrug, Lutein Diglutaric Acid, against H₂O₂-Induced Oxidative Stress in Human Retinal Pigment Epithelial Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (9). 4722-.

Butler, Joe M, Supharattanasitthi, Wasu, Yang, Yit C and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2021) RNA-seq analysis of ageing human retinal pigment epithelium: Unexpected up-regulation of visual cycle gene transcription. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 25 (12). pp. 5572-5585.

Paraoan, Luminita ORCID: 0000-0001-7568-7116, Sharif, Umar, Carlsson, Emil, Supharattanasitthi, Wasu, Mahmud, Nur Musfirah, Kamalden, Tengku Ain, Hiscott, Paul ORCID: 0000-0002-4273-2387, Jackson, Malcolm ORCID: 0000-0003-3683-8297 and Grierson, Ian (2020) Secretory proteostasis of the retinal pigmented epithelium: Impairment links to age-related macular degeneration. PROGRESS IN RETINAL AND EYE RESEARCH, 79. 100859-.

McDonnell, SJ (2018) Study of novel protein-protein interactions modulating PERP-mediated apoptosis. PhD thesis, University of Liverpool.

Mahmud, Nur Musfirah, Paraoan, Luminita ORCID: 0000-0001-7568-7116, Khaliddin, Nurliza and Kamalden, Tengku Ain (2022) Thymoquinone in Ocular Neurodegeneration: Modulation of Pathological Mechanisms via Multiple Pathways. FRONTIERS IN CELLULAR NEUROSCIENCE, 16. 786926-.

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Porter, Louise Frances, Saptarshi, Neil, Fang, Yongxiang, Rathi, Sonika, Den Hollander, Anneke I, de Jong, Eiko, Clark, Simon, Bishop, Paul N, Olsen, Timothy W, Liloglu, Triantafillos et al (show 2 more authors) , Chavali, Venkata Ramana Murthy and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2019) Whole genome methylation profiling of retinal pigment epithelium reveals differential methylation and gene expression associated with AMD. In: ARVO annual meeting, Vancouver, Canada.

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Porter, Louise F ORCID: 0000-0002-7406-0319, Saptarshi, Neil, Fang, Yongxiang ORCID: 0000-0002-4514-5292, Rathi, Sonika, den Hollander, Anneke I, de Jong, Eiko K, Clark, Simon J, Bishop, Paul N, Olsen, Timothy W, Liloglou, Triantafillos ORCID: 0000-0003-0460-1404 et al (show 2 more authors) , Chavali, Venkata RM and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2019) Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes. Clinical epigenetics, 11 (1). p. 6.

Pollock, Natalie ORCID: 0000-0002-4969-5486 The incidence of cross-linked actin networks (CLANs)in the trabecular meshwork of the ageing eye. Doctor of Philosophy thesis, University of Liverpool.

Chatsirisupachai, Kasit ORCID: 0000-0001-9446-6714, Lesluyes, Tom, Paraoan, Luminita ORCID: 0000-0001-7568-7116, Van Loo, Peter and de Magalhães, João Pedro ORCID: 0000-0002-6363-2465 (2021) An integrative analysis of the age-associated multi-omic landscape across cancers. Nature Communications, 12 (1). 2345-.

Butler, Joe M, Sharif, Umar, Ali, Manir, McKibbin, Martin, Thompson, Joseph P, Gale, Richard, Yang, Yit C, Inglehearn, Chris and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2015) A missense variant in <i>CST3</i> exerts a recessive effect on susceptibility to age-related macular degeneration resembling its association with Alzheimer's disease. HUMAN GENETICS, 134 (7). pp. 705-715.

Dhirachaikulpanich, Dhanach ORCID: 0000-0003-2234-1837, Paraoan, Robert AI, Carlsson, Emil and Paraoan, Luminita ORCID: 0000-0001-7568-7116 (2020) The quest of vision: retina’s daily challenges. The Biochemist, 42 (5). pp. 4-10.