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Number of items: 33.


de Knegt, Gerjo J, Dickinson, Laura ORCID: 0000-0001-5557-9396, Pertinez, Henry, Evangelopoulos, Dimitrios, McHugh, Timothy D, Bakker-Woudenberg, Irma AJM, Davies, Gerry R ORCID: 0000-0002-3819-490X and de Steenwinkel, Jurriaan EM
(2017) Assessment of treatment response by colony forming units, time to culture positivity and the molecular bacterial load assay compared in a mouse tuberculosis model. TUBERCULOSIS, 105. pp. 113-118.


Hu, Yanmin, Pertinez, Henry, Liu, Yingjun, Davies, Geraint ORCID: 0000-0002-3819-490X and Coates, Anthony
(2019) Bedaquiline kills persistent <i>Mycobacterium tuberculosis</i> with no disease relapse: an <i>in vivo</i> model of a potential cure. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 74 (6). pp. 1627-1633.


Gallardo-Toledo, Eduardo ORCID: 0009-0000-8534-9030, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne ORCID: 0000-0001-8482-5736, Herriott, Joanne, Kijak, Edyta, Bramwell, Chloe ORCID: 0000-0001-8274-457X, Curley, Paul ORCID: 0000-0003-4596-2708, Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712
et al (show 6 more authors) (2023) Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters. Viruses, 15 (11). 2161-.


Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Pertinez, Henry, Arshad, Usman ORCID: 0000-0003-1586-1885, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Valentijn, Anthony
et al (show 13 more authors) (2021) Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87 (4). pp. 2078-2088.


Rajoli, Rajith Kr ORCID: 0000-0002-6015-5712, Pertinez, Henry, Arshad, Usman ORCID: 0000-0003-1586-1885, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne ORCID: 0000-0001-8482-5736, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Valentijn, Anthony
et al (show 13 more authors) (2020) Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis. medRxiv : the preprint server for health sciences, 1 (06-05). 2020.05.01.20087130-.


Velasquez, Gustavo E, Brooks, Meredith B, Coit, Julia M, Pertinez, Henry, Vasquez, Dante Vargas, Garavito, Epifano Sanchez, Calderon, Roger I, Jimenez, Judith, Tintaya, Karen, Peloquin, Charles A
et al (show 6 more authors) (2018) Efficacy and Safety of High-Dose Rifampin in Pulmonary Tuberculosis. A Randomized Controlled Trial. American Journal of Respiratory and Critical Care Medicine, 198 (5). pp. 657-666.


Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Gallardo-Toledo, Eduardo, Herriott, Joanne, Kijak, Edyta, Bramwell, Chloe, Cox, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Box, Helen, Curley, Paul ORCID: 0000-0003-4596-2708
et al (show 11 more authors) (2023) Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters. VIRUSES-BASEL, 15 (8). 1744-.


Yip, Vincent LM ORCID: 0000-0003-1640-2816, Pertinez, Henry, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Maggs, James L, Carr, Daniel F, Park, B Kevin ORCID: 0000-0001-8384-824X, Marson, Anthony G ORCID: 0000-0002-6861-8806 and Pirmohamed, Munir ORCID: 0000-0002-7534-7266
(2021) Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87 (6). pp. 2572-2588.


Brevini, Teresa, Maes, Mailis, Webb, Gwilym J, John, Binu V, Fuchs, Claudia D, Buescher, Gustav, Wang, Lu, Griffiths, Chelsea, Brown, Marnie L, Scott, William EIII
et al (show 69 more authors) (2023) FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2. NATURE, 615 (7950). 134-+.


Dickinson, Laura ORCID: 0000-0001-5557-9396, Walimbwa, Stephen, Singh, Yashna, Kaboggoza, Julian, Kintu, Kenneth, Sihlangu, Mary, Coombs, Julie-Anne, Malaba, Thokozile R, Byamugisha, Josaphat, Pertinez, Henry
et al (show 11 more authors) (2021) Infant Exposure to Dolutegravir Through Placental and Breast Milk Transfer: A Population Pharmacokinetic Analysis of DolPHIN-1. CLINICAL INFECTIOUS DISEASES, 73 (5). E1200-E1207.


Hu, Yanmin, Pertinez, Henry, Ortega-Muro, Fatima, Alameda-Martin, Laura, Liu, Yingjun, Schipani, Alessandro, Davies, Geraint ORCID: 0000-0002-3819-490X and Coates, Anthony
(2016) Investigation of Elimination Rate, Persistent Subpopulation Removal, and Relapse Rates of Mycobacterium tuberculosis by Using Combinations of First-Line Drugs in a Modified Cornell Mouse Model. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 60 (8). pp. 4778-4785.


Box, Helen J, Sharp, Joanne, Pennington, Shaun H, Kijak, Edyta, Tatham, Lee ORCID: 0000-0001-9448-8876, Caygill, Claire H, Lopeman, Rose C, Jeffreys, Laura N, Herriott, Joanne, Neary, Megan
et al (show 15 more authors) (2023) Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters. The Journal of antimicrobial chemotherapy, 79 (1). dkad362-dkad362.


Millard, James ORCID: 0000-0001-6427-552X, Pertinez, Henry, Bonnett, Laura ORCID: 0000-0002-6981-9212, Hodel, Eva Maria ORCID: 0000-0001-5821-1685, Dartois, Veronique, Johnson, John L, Caws, Maxine, Tiberi, Simon, Bolhuis, Mathieu, Alffenaar, Jan-Willem C
et al (show 2 more authors) (2018) Linezolid pharmacokinetics in MDR-TB: a systematic review, meta-analysis and Monte Carlo simulation. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 73 (7). pp. 1755-1762.


Liu, Yingjun, Pertinez, Henry, Davies, Geraint R ORCID: 0000-0002-3819-490X, Gillespie, Stephen H, Coates, Anthony R and Hua, Yanmin
(2018) Moxifloxacin Replacement in Contemporary Tuberculosis Drug Regimens Is Ineffective against Persistent<i> Mycobacterium tuberculosis</i> in the Cornell Mouse Model. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62 (7). e00190-e00118.


Walker, Lauren E ORCID: 0000-0002-3827-4387, FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin
et al (show 23 more authors) (2022) An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2. CLINICAL PHARMACOLOGY & THERAPEUTICS, 111 (3). pp. 585-594.


Khoo, Saye H ORCID: 0000-0002-2769-0967, Fitzgerald, Richard, Fletcher, Thomas, Ewings, Sean, Jaki, Thomas, Lyon, Rebecca, Downs, Nichola, Walker, Lauren ORCID: 0000-0002-3827-4387, Tansley-Hancock, Olana, Greenhalf, William
et al (show 28 more authors) (2021) Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76 (12). pp. 3286-3295.


Liu, Yingjun, Pertinez, Henry, Ortega-Muro, Fatima, Alameda-Martin, Laura, Harrison, Thomas, Davies, Geraint ORCID: 0000-0002-3819-490X, Coates, Anthony and Hu, Yanmin
(2018) Optimal doses of rifampicin in the standard drug regimen to shorten tuberculosis treatment duration and reduce relapse by eradicating persistent bacteria. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 73 (3). pp. 724-731.


Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne ORCID: 0000-0001-8482-5736, Valentijn, Anthony, Hobson, James ORCID: 0000-0003-2551-1774, Unsworth, Catherine ORCID: 0000-0002-2748-8283
et al (show 6 more authors) (2021) Optimisation and validation of a sensitive bioanalytical method for niclosamide. [Preprint]


Pertinez, Henry, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Khoo, Saye H ORCID: 0000-0002-2769-0967 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2021) Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5′-triphosphate exposure to support posology for SARS-CoV-2. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76 (8). pp. 2121-2128.


Kinvig, Hannah, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Pertinez, Henry, Vora, Lalitkumar K, Volpe-Zanutto, Fabiana, Donnelly, Ryan F, Rannard, Steve ORCID: 0000-0002-6946-1097, Flexner, Charles, Siccardi, Marco ORCID: 0000-0002-3539-7867 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2023) Physiologically Based Pharmacokinetic Modelling of Cabotegravir Microarray Patches in Rats and Humans. Pharmaceutics, 15 (12). p. 2709.


Turkistani, AA
(2019) Population Pharmacokinetic and Pharmacodynamic Modelling to Describe the Effects of APAP Overdose on Novel Biomarkers in UK Patients. PhD thesis, University of Liverpool.


Curley, Paul, Hobson, James J ORCID: 0000-0003-2551-1774, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Makarov, Edward, Al-Khouja, Amer, Tatham, Lee ORCID: 0000-0001-9448-8876, David, Christopher AW ORCID: 0000-0001-8504-2354, Box, Helen, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne
et al (show 7 more authors) (2023) Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations. Pharmaceutics, 15 (7). p. 1835.


Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Rajoli, Rajith Kr ORCID: 0000-0002-6015-5712, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Valentijn, Anthony
et al (show 12 more authors) (2020) Prioritisation of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics. Clinical pharmacology and therapeutics, 108 (4). pp. 775-790.


Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Box, Helen, Tatham, Lee, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan, Sharp, Joanne, Liptrott, Neill ORCID: 0000-0002-5980-8966, Valentijn, Anthony
et al (show 11 more authors) (2020) Prioritisation of potential anti-SARS-CoV-2 drug repurposing opportunities based on ability to achieve adequate plasma and target site concentrations derived from their established human pharmacokinetics. Clinical Pharmacology and Therapeutics. 2020.04.16.20068379-.


Neary, Megan ORCID: 0000-0002-4960-2139, Arshad, Usman ORCID: 0000-0003-1586-1885, Tatham, Lee ORCID: 0000-0001-9448-8876, Pertinez, Henry, Box, Helen, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Valentijn, Anthony, Sharp, Joanne ORCID: 0000-0001-8482-5736, Rannard, Steve ORCID: 0000-0002-6946-1097, Biagini, Giancarlo ORCID: 0000-0001-6356-6595
et al (show 2 more authors) (2021) Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research. [Preprint]


Neary, Megan ORCID: 0000-0002-4960-2139, Arshad, Usman ORCID: 0000-0003-1586-1885, Tatham, Lee ORCID: 0000-0001-9448-8876, Pertinez, Henry, Box, Helen, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Valentijn, Anthony, Sharp, Joanne, Rannard, Steve P ORCID: 0000-0002-6946-1097, Biagini, Giancarlo A
et al (show 2 more authors) (2023) Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1228. 123823-.


Hendon-Dunn, Charlotte L, Pertinez, Henry, Marriott, Alice AN, Hatch, Kim A, Allnutt, Jon C, Davies, Geraint and Bacon, Joanna
(2019) Regrowth of <i>Mycobacterium</i> <i>tuberculosis</i> Populations Exposed to Antibiotic Combinations Is Due to the Presence of Isoniazid and Not Bacterial Growth Rate. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63 (12). AAC.00570-AAC.00519.


Hobson, James Joseph ORCID: 0000-0003-2551-1774, Savage, Alison Clare ORCID: 0000-0002-5312-9946, Dwyer, Andrew, Unsworth, Catherine, Massam, Jonathan, Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Box, Helen, Tatham, Lee M ORCID: 0000-0001-9448-8876, Rajoli, Rajith ORCID: 0000-0002-6015-5712
et al (show 9 more authors) (2021) Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection. Nanoscale, 13 (13). pp. 6410-6416.


Hobson, James ORCID: 0000-0003-2551-1774, Savage, Alison, Dwyer, Andrew, Unsworth, Catherine, Arshad, Usman, Pertinez, Henry, box, helen, Tatham, Lee, Rajoli, Rajith ORCID: 0000-0002-6015-5712, Neary, Megan ORCID: 0000-0002-4960-2139
et al (show 8 more authors) (2021) Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection. Unknown.


Hobson, James ORCID: 0000-0003-2551-1774, Savage, Alison, Dwyer, Andrew, Unsworth, Catherine, Arshad, Usman, Pertinez, Henry, box, helen, Tatham, Lee, Rajoli, Rajith KR, Neary, Megan
et al (show 8 more authors) (2021) Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection.


Chang, Yong S, Li, Si-Yang, Pertinez, Henry, Betoudji, Fabrice, Lee, Jin, Rannard, Steven P ORCID: 0000-0002-6946-1097, Owen, Andrew ORCID: 0000-0002-9819-7651, Nuermberger, Eric L and Ammerman, Nicole C
(2023) Using Dynamic Oral Dosing of Rifapentine and Rifabutin to Simulate Exposure Profiles of Long-Acting Formulations in a Mouse Model of Tuberculosis Preventive Therapy. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 67 (7). e0048123-.


Wootton, Daniel G ORCID: 0000-0002-5903-3881, Dickinson, Laura ORCID: 0000-0001-5557-9396, Pertinez, Henry, Court, Joanne, Eneje, Odiri, Keogan, Lynne, Macfarlane, Laura, Wilks, Sarah, Gallagher, Jane, Woodhead, Mark
et al (show 2 more authors) (2017) A longitudinal modelling study estimates acute symptoms of community acquired pneumonia recover to baseline by 10 days. European Respiratory Journal, 49 (6). 1602170-.


Schipani, Alessandro, Pertinez, Henry, Mlota, Rachel, Molyneux, Elizabeth, Lopez, Nuria, Dzinjalamala, Fraction K, van Oosterhout, Joep J, Ward, Steve A, Khoo, Saye ORCID: 0000-0002-2769-0967 and Davies, Gerry ORCID: 0000-0002-3819-490X
(2016) A simultaneous population pharmacokinetic analysis of rifampicin in Malawian adults and children. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 81 (4). pp. 679-687.

This list was generated on Sun Mar 17 13:41:49 2024 GMT.