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Number of items: 24.


Gallardo-Toledo, Eduardo ORCID: 0009-0000-8534-9030, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne ORCID: 0000-0001-8482-5736, Herriott, Joanne, Kijak, Edyta, Bramwell, Chloe ORCID: 0000-0001-8274-457X, Curley, Paul ORCID: 0000-0003-4596-2708, Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712
et al (show 6 more authors) (2023) Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters. Viruses, 15 (11). 2161-.


Cottura, Nicolas ORCID: 0000-0003-3083-2249, Howarth, Alice ORCID: 0000-0003-2288-1745, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2020) The Current Landscape of Novel Formulations and the Role of Mathematical Modeling in Their Development. JOURNAL OF CLINICAL PHARMACOLOGY, 60 (S1). S77-S97.


Chan, Christina YS, Roberts, Owain, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Siccardi, Marco ORCID: 0000-0002-3539-7867, Almond, Lisa and Owen, Andrew ORCID: 0000-0002-9819-7651
(2018) Derivation of CYP3A4 and CYP2B6 degradation rate constants in primary human hepatocytes: A siRNA-silencing-based approach. DRUG METABOLISM AND PHARMACOKINETICS, 33 (4). pp. 179-187.


Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Pertinez, Henry, Arshad, Usman ORCID: 0000-0003-1586-1885, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Valentijn, Anthony
et al (show 13 more authors) (2021) Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87 (4). pp. 2078-2088.


Curley, Paul ORCID: 0000-0003-4596-2708, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Moss, Darren M, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Letendre, Scott, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2017) Efavirenz Is Predicted To Accumulate in Brain Tissue: an <i>In Silico</i>, <i>In Vitro</i>, and <i>In Vivo</i> Investigation. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (1). e01841-e01816.


Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Gallardo-Toledo, Eduardo, Herriott, Joanne, Kijak, Edyta, Bramwell, Chloe, Cox, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Box, Helen, Curley, Paul ORCID: 0000-0003-4596-2708
et al (show 11 more authors) (2023) Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters. VIRUSES-BASEL, 15 (8). 1744-.


Box, Helen J, Sharp, Joanne, Pennington, Shaun H, Kijak, Edyta, Tatham, Lee ORCID: 0000-0001-9448-8876, Caygill, Claire H, Lopeman, Rose C, Jeffreys, Laura N, Herriott, Joanne, Neary, Megan
et al (show 15 more authors) (2023) Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters. The Journal of antimicrobial chemotherapy. dkad362-dkad362.


Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Flexner, Charles, Chiong, Justin ORCID: 0000-0001-8063-6399, Owen, Andrew ORCID: 0000-0002-9819-7651, Donnelly, Ryan F, Larraneta, Eneko and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2019) Modelling the intradermal delivery of microneedle array patches for long-acting antiretrovirals using PBPK. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 144. pp. 101-109.


Walker, Lauren E ORCID: 0000-0002-3827-4387, FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin
et al (show 23 more authors) (2022) An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2. CLINICAL PHARMACOLOGY & THERAPEUTICS, 111 (3). pp. 585-594.


Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Valentijn, Anthony, Hobson, James ORCID: 0000-0003-2551-1774, Unsworth, Catherine
et al (show 6 more authors) (2021) Optimisation and validation of a sensitive bioanalytical method for niclosamide. [Preprint]


Pertinez, Henry, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Khoo, Saye H ORCID: 0000-0002-2769-0967 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2021) Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5′-triphosphate exposure to support posology for SARS-CoV-2. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76 (8). pp. 2121-2128.


Roberts, Owain, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Back, David J, Owen, Andrew ORCID: 0000-0002-9819-7651, Darin, Kristin M, Fletcher, Courtney V, Lamorde, Mohammed, Scarsi, Kimberly K and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2018) Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug–drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART. Journal of Antimicrobial Chemotherapy, 73 (4). pp. 1004-1012.


Saeheng, Teerachat, Na-Bangchang, Kesara, Siccardi, Marco ORCID: 0000-0002-3539-7867, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712 and Karbwang, Juntra
(2020) Physiologically-Based Pharmacokinetic Modeling for Optimal Dosage Prediction of Quinine Coadministered With Ritonavir-Boosted Lopinavir. CLINICAL PHARMACOLOGY & THERAPEUTICS, 107 (5). pp. 1209-1220.


Olagunju, A ORCID: 0000-0002-6588-5749, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Atoyebi, Shakir Adeyinka, Khoo, Saye ORCID: 0000-0002-2769-0967, Owen, Andrew and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2018) Physiologically-based pharmacokinetic modelling of infant exposure to efavirenz through breastfeeding. AAS Open Research, 1 (16).


Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Curley, Paul ORCID: 0000-0003-4596-2708, Chiong, Justin ORCID: 0000-0001-8063-6399, Back, David, Flexner, Charles, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2019) Predicting Drug-Drug Interactions Between Rifampicin and Long-Acting Cabotegravir and Rilpivirine Using Physiologically Based Pharmacokinetic Modeling. JOURNAL OF INFECTIOUS DISEASES, 219 (11). pp. 1735-1742.


Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Demkovich, Zach R, Flexner, Charles, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2020) Predicting pharmacokinetics of a tenofovir alafenamide subcutaneous implant using PBPK modelling. Antimicrobial Agents and Chemotherapy, 64 (8). e00155-e00120.


Bunglawala, Fazila, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Mirochnick, Mark, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2020) Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 75 (3). pp. 640-647.


Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Box, Helen, Tatham, Lee, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan, Sharp, Joanne, Liptrott, Neill ORCID: 0000-0002-5980-8966, Valentijn, Anthony
et al (show 11 more authors) (2020) Prioritisation of potential anti-SARS-CoV-2 drug repurposing opportunities based on ability to achieve adequate plasma and target site concentrations derived from their established human pharmacokinetics. Clinical Pharmacology and Therapeutics.


Neary, Megan ORCID: 0000-0002-4960-2139, Arshad, Usman ORCID: 0000-0003-1586-1885, Tatham, Lee ORCID: 0000-0001-9448-8876, Pertinez, Henry, Box, Helen, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Valentijn, Anthony, Sharp, Joanne, Rannard, Steve ORCID: 0000-0002-6946-1097, Biagini, Giancarlo ORCID: 0000-0001-6356-6595
et al (show 2 more authors) (2021) Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research. [Preprint]


Neary, Megan ORCID: 0000-0002-4960-2139, Arshad, Usman ORCID: 0000-0003-1586-1885, Tatham, Lee ORCID: 0000-0001-9448-8876, Pertinez, Henry, Box, Helen, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Valentijn, Anthony, Sharp, Joanne, Rannard, Steve P ORCID: 0000-0002-6946-1097, Biagini, Giancarlo A
et al (show 2 more authors) (2023) Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1228. 123823-.


Hobson, James ORCID: 0000-0003-2551-1774, Savage, Alison, Dwyer, Andrew, Unsworth, Catherine, Arshad, Usman, Pertinez, Henry, box, helen, Tatham, Lee, Rajoli, Rajith KR, Neary, Megan
et al (show 8 more authors) (2021) Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection.


Sacramento, Carolina Q, Fintelman-Rodrigues, Natalia, Dias, Suelen SG, Temerozo, Jairo R, Da Silva, Aline de Paula D, da Silva, Carine S, Blanco, Camilla, Ferreira, Andre C, Mattos, Mayara, Soares, Vinicius C
et al (show 13 more authors) (2022) Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells. VIRUSES-BASEL, 14 (2). 374-.


Atoyebi, Shakir Adeyinka ORCID: 0000-0002-1393-3753, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Adejuyigbe, Ebunoluwa, Owen, Andrew ORCID: 0000-0002-9819-7651, Bolaji, Oluseye, Siccardi, Marco ORCID: 0000-0002-3539-7867 and Olagunju, Adeniyi ORCID: 0000-0002-6588-5749
(2019) Using mechanistic physiologically-based pharmacokinetic models to assess prenatal drug exposure: Thalidomide <i>versus</i> efavirenz as case studies. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 140. 105068-.


Sacramento, Carolina Q, Fintelman-Rodrigues, Natalia, Temerozo, Jairo R, Dias Da Silva, Aline de Paula, Gomes Dias, Suelen da Silva, da Silva, Carine dos Santos, Ferreira, Andre C, Mattos, Mayara, Pao, Camila RR, de Freitas, Caroline S
et al (show 30 more authors) (2021) <i>In vitro</i> antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76 (7). pp. 1874-1885.

This list was generated on Sat Dec 23 04:22:26 2023 GMT.