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Soares, Pedro ORCID: 0000-0002-5755-1757, Gadd, Morgan S ORCID: 0000-0001-6124-0858, Frost, Julianty, Galdeano, Carles, Ellis, Lucy, Epemolu, Ola, Rocha, Sonia ORCID: 0000-0002-2413-4981, Read, Kevin D and Ciulli, Alessio ORCID: 0000-0002-8654-1670
(2018) Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298). Journal of medicinal chemistry, 61 (2). 599 - 618.


Frost, Julianty, Galdeano, Carles, Soares, Pedro, Gadd, Morgan S, Grzes, Katarzyna M, Ellis, Lucy, Epemolu, Ola, Shimamura, Satoko, Bantscheff, Marcus, Grandi, Paola
et al (show 4 more authors) (2016) Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition. Nature communications, 7.


De Rycker, Manu, Horn, David, Aldridge, Bree, Amewu, Richard K, III, Barry Clifton E, Buckner, Frederick S, Cook, Sarah, Ferguson, Michael AJ, Gobeau, Nathalie, Herrmann, Jennifer
et al (show 27 more authors) (2020) Setting Our Sights on Infectious Diseases. ACS INFECTIOUS DISEASES, 6 (1). 3 - 13.


Zhang, Shaowei, Sakuma, Michiyo, Deora, Girdhar S, Levy, Colin W, Klausing, Alex, Breda, Carlo, Read, Kevin D, Edlin, Chris D, Ross, Benjamin P, Muelas, Marina Wright
et al (show 8 more authors) (2019) A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. COMMUNICATIONS BIOLOGY, 2.

This list was generated on Mon Nov 23 13:08:27 2020 GMT.