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Number of items: 43.


Ortmann, Brian, Bensaddek, Dalila, Carvalhal, Sara, Moser, Sandra C, Mudie, Sharon, Griffis, Eric R, Swedlow, Jason R, Lamond, Angus I and Rocha, Sonia
(2016) CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. Journal of cell science, 129 (1). pp. 191-205.


Wiechens, Nicola, Singh, Vijender, Gkikopoulos, Triantaffyllos, Schofield, Pieta ORCID: 0000-0002-6398-2537, Rocha, Sonia and Owen-Hughes, Tom
(2016) The Chromatin Remodelling Enzymes SNF2H and SNF2L Position Nucleosomes adjacent to CTCF and Other Transcription Factors. PLOS GENETICS, 12 (3). e1005940-.


Jiang, Yifan, He, Chao ORCID: 0000-0002-9023-1595, Ye, Haokai, Xu, Qianhan, Chen, Xiuyuan, Chen, Ying, Sun, Jianying, Rocha, Sonia ORCID: 0000-0002-2413-4981 and Wang, Mu ORCID: 0009-0007-3584-6873
(2023) Comprehensive analysis of the lysine succinylome in fish oil-treated prostate cancer cells. Life science alliance, 6 (11). e202302131-.


Hunter, Jill, McHugh, Oliver, Ecclestone, Gabrielle, Child, Fraser, Mearns, Hannah, Robson, Georgia, Dadzie, Molly, Rocha, Sonia ORCID: 0000-0002-2413-4981, Perkins, Neil and Kenneth, Niall ORCID: 0000-0001-8528-1021
(2022) Disruption of HIF1Α translational control attenuates the HIF-dependent hypoxic response and solid tumour formation<i>in vivo</i>. [Preprint]


Myronenko, Oleh ORCID: 0000-0001-5221-7218, Foris, Vasile, Crnkovic, Slaven, Olschewski, Andrea ORCID: 0000-0002-8189-3634, Rocha, Sonia, Nicolls, Mark R ORCID: 0000-0001-9473-7422 and Olschewski, Horst
(2023) Endotyping COPD: hypoxia-inducible factor-2 as a molecular "switch" between the vascular and airway phenotypes? European respiratory review : an official journal of the European Respiratory Society, 32 (167). 220173-.


Ono, Motoharu, Yamada, Kayo, Bensaddek, Dalila, Afzal, Vackar, Biddlestone, John, Ortmann, Brian ORCID: 0000-0002-3639-0691, Mudie, Sharon, Boivin, Vincent ORCID: 0000-0001-6434-2737, Scott, Michelle S, Rocha, Sonia ORCID: 0000-0002-2413-4981
et al (show 1 more authors) (2016) Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines. PloS one, 11 (4). e0154759-.


Fok, Matthew ORCID: 0000-0003-4091-6569, Hill, Rhianna, Fowler, Hayley, Clifford, Rachael, Kler, Aaron, Uzzi-Daniel, Jayanma, Rocha, Sonia, Grundy, Gabrielle ORCID: 0000-0003-1506-3664, Parsons, Jason and Vimalachandran, Dale ORCID: 0000-0001-5817-8969
(2023) Enhancing radiotherapy outcomes in rectal cancer: A systematic review of targeting hypoxia-induced radioresistance. Clinical and Translational Radiation Oncology, 44. p. 100695.


Shakir, Dilem, Batie, Michael ORCID: 0000-0002-7508-6641 and Rocha, Sonia
(2023) Fixed Cell Immunofluorescence for Quantification of Hypoxia-Induced Changes in Histone Methylation. Methods in molecular biology (Clifton, N.J.), 2675. pp. 261-269.


Collier, Harry, Albanese, Adam, Kwok, Chun-Sui, Kou, Jiahua and Rocha, Sonia
(2023) Functional crosstalk between chromatin and hypoxia signalling. CELLULAR SIGNALLING, 106. 110660-.


Batie, Michael ORCID: 0000-0002-7508-6641 and Rocha, Sonia
(2020) Gene transcription and chromatin regulation in hypoxia. Biochemical Society transactions, 48 (3). pp. 1121-1128.


Soares, Pedro, Gadd, Morgan S, Frost, Julianty ORCID: 0000-0001-8209-2575, Galdeano, Carles, Ellis, Lucy, Epemolu, Ola, Rocha, Sonia, Read, Kevin D and Ciulli, Alessio
(2018) Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2<i>S</i>,4<i>R</i>)-1-((<i>S</i>)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyI)-4-hydroxy-<i>N</i>-(4-(4-methylthiazol-5-yl)benzyppyrrolidine-2-carboxamide (VH298). JOURNAL OF MEDICINAL CHEMISTRY, 61 (2). pp. 599-618.


Klionsky, Daniel J, Abdelmohsen, Kotb, Abe, Akihisa, Abedin, Md Joynal, Abeliovich, Hagai, Arozena, Abraham Acevedo, Adachi, Hiroaki, Adams, Christopher M, Adams, Peter D, Adeli, Khosrow
et al (show 2450 more authors) (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). AUTOPHAGY, 12 (1). pp. 1-222.


D'Ignazio, Laura, Shakir, Dilem, Batie, Michael ORCID: 0000-0002-7508-6641, Muller, H Arno and Rocha, Sonia
(2020) HIF-1beta Positively Regulates NF-kappaB Activity via Direct Control of TRAF6. International Journal of Molecular Sciences, 21 (8).


D'Ignazio, Laura, Shakir, Dilem, Batie, Michael ORCID: 0000-0002-7508-6641, Muller, H Arno and Rocha, Sonia
(2020) HIF-1β Positively Regulates NF-κB Activity via Direct Control of TRAF6. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21 (8). E3000-.


Maniaci, Chiara, Hughes, Scott J, Testa, Andrea, Chen, Wenzhang, Lamont, Douglas J, Rocha, Sonia, Alessi, Dario R, Romeo, Roberto and Ciulli, Alessio
(2017) Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nature communications, 8 (1). 830-.


Batie, Michael ORCID: 0000-0002-7508-6641, Frost, Julianty ORCID: 0000-0001-8209-2575, Frost, Mark ORCID: 0000-0001-7209-2897, Wilson, James W ORCID: 0000-0002-9373-6919, Schofield, Pieta ORCID: 0000-0002-6398-2537 and Rocha, Sonia
(2019) Hypoxia Induces Rapid Changes to Histone Methylation and Reprograms Chromatin. Science, 363 (6432). pp. 1222-1226.


Batie, Michael, del Peso, Luis and Rocha, Sonia ORCID: 0000-0002-2413-4981
(2018) Hypoxia and Chromatin, a Focus on Transcriptional Repression Mechanisms. Biomedicines.


Batie, Michael ORCID: 0000-0002-7508-6641, del Peso, Luis and Rocha, Sonia
(2018) Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms. BIOMEDICINES, 6 (2). p. 47.


D'Ignazio, Laura ORCID: 0000-0002-1707-4773, Batie, Michael ORCID: 0000-0002-7508-6641 and Rocha, Sonia ORCID: 0000-0002-2413-4981
(2017) Hypoxia and Inflammation in Cancer, Focus on HIF and NF-κB. Biomedicines, 5 (2). E21-.


D'Ignazio, Laura, Batie, Michael and Rocha, Sonia ORCID: 0000-0002-2413-4981
(2017) Hypoxia and Inflammation in Cancer, Focus on HIF and NF-кB.


Batie, Michael, Frost, Julianty, Frost, Mark, Wilson, James, Schofield, Pieta ORCID: 0000-0002-6398-2537 and Rocha, Sonia ORCID: 0000-0002-2413-4981
(2019) Hypoxia induces rapid changes to histone methylation reprogramming chromatin for the cellular response: Supplementary material. bioRxiv. p. 513069.


Batie, Michael ORCID: 0000-0002-7508-6641, Druker, Jimena, D'Ignazio, Laura and Rocha, Sonia
(2017) KDM2 Family Members are Regulated by HIF-1 in Hypoxia. CELLS, 6 (1). E8-.


Hill, Rhianna M, Rocha, Sonia and Parsons, Jason L ORCID: 0000-0002-5052-1125
(2022) Overcoming the Impact of Hypoxia in Driving Radiotherapy Resistance in Head and Neck Squamous Cell Carcinoma. Cancers, 14 (17). p. 4130.


Daly, Leonard A ORCID: 0000-0001-9712-9676, Brownridge, Philip J, Batie, Michael ORCID: 0000-0002-7508-6641, Rocha, Sonia, See, Violaine ORCID: 0000-0001-6384-8381 and Eyers, Claire E ORCID: 0000-0002-3223-5926
(2021) Oxygen-dependent changes in binding partners and post-translational modifications regulate the abundance and activity of HIF-1 alpha/2 alpha. SCIENCE SIGNALING, 14 (692). eabf6685-.


Batie, Michael ORCID: 0000-0002-7508-6641, Fasanya, Temitope ORCID: 0009-0007-2107-8578, Kenneth, Niall S ORCID: 0000-0001-8528-1021 and Rocha, Sonia
(2023) Oxygen-regulated post-translation modifications as master signalling pathway in cells. EMBO reports, 24 (12). e57849-e57849.


Wilson, James W ORCID: 0000-0002-9373-6919, Shakir, Dilem, Batie, Michael ORCID: 0000-0002-7508-6641, Frost, Mark ORCID: 0000-0001-7209-2897 and Rocha, Sonia
(2020) Oxygen-sensing mechanisms in cells. FEBS JOURNAL, 287 (18). pp. 3888-3906.


Shmakova, Alena, Frost, Mark, Batie, Michael ORCID: 0000-0002-7508-6641, Kenneth, Niall S ORCID: 0000-0001-8528-1021 and Rocha, Sonia
(2021) PBRM1 Cooperates with YTHDF2 to Control HIF-1 alpha Protein Translation. CELLS, 10 (6). 1425-.


Shmakova, Alena, Frost, Mark, Kenneth, Niall and Rocha, Sonia ORCID: 0000-0002-2413-4981
(2021) PBRM1 Cooperates with YTHDF2 to Control HIF-1Alpha Protein Translation. Cells.


Frost, Julianty ORCID: 0000-0001-8209-2575, Galdeano, Carles, Soares, Pedro, Gadd, Morgan S, Grzes, Katarzyna M, Ellis, Lucy, Epemolu, Ola, Shimamura, Satoko, Bantscheff, Marcus, Grandi, Paola
et al (show 4 more authors) (2016) Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition. Nature communications, 7 (1).


Frost, Julianty ORCID: 0000-0001-8209-2575, Ciulli, Alessio ORCID: 0000-0002-8654-1670 and Rocha, Sonia ORCID: 0000-0002-2413-4981
(2019) RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response. Wellcome open research, 4. 17-.


Batie, Michael ORCID: 0000-0002-7508-6641, Frost, Julianty ORCID: 0000-0001-8209-2575, Shakir, Dilem and Rocha, Sonia
(2022) Regulation of chromatin accessibility by hypoxia and HIF. BIOCHEMICAL JOURNAL, 479 (6). pp. 767-786.


Batie, Michael, Frost, Julianty, Shakir, Dilem and Rocha, Sonia ORCID: 0000-0002-2413-4981
(2022) Regulation of chromatin accessibility by hypoxia and HIF. The Biochemical journal, 479 (6). 767 - 786.


Druker, Jimena, Wilson, James W ORCID: 0000-0002-9373-6919, Child, Fraser, Shakir, Dilem, Fasanya, Temitope and Rocha, Sonia
(2021) Role of Hypoxia in the Control of the Cell Cycle. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (9). 4874-.


Frost, Julianty, Frost, Mark, Batie, Michael, Jiang, Hao and Rocha, Sonia ORCID: 0000-0002-2413-4981
(2020) Roles Of HIF and 2-Oxoglutarate Dependent Enzymes in Controlling Gene Expression In Hypoxia. Cancers.


Frost, Julianty ORCID: 0000-0001-8209-2575, Frost, Mark ORCID: 0000-0001-7209-2897, Batie, Michael ORCID: 0000-0002-7508-6641, Jiang, Hao and Rocha, Sonia
(2021) Roles of HIF and 2-Oxoglutarate-Dependent Dioxygenases in Controlling Gene Expression in Hypoxia. CANCERS, 13 (2). 350-.


Biddlestone, John, Batie, Michael ORCID: 0000-0002-7508-6641, Bandarra, Daniel, Munoz, Ivan and Rocha, Sonia
(2018) SINHCAF/FAM60A and SIN3A specifically repress HIF-2α expression. BIOCHEMICAL JOURNAL, 475 (12). pp. 2073-2090.


D'Ignazio, Laura, Batie, Michael and Rocha, Sonia ORCID: 0000-0002-2413-4981
(2018) TNFSF14/LIGHT, a Non-Canonical NF-kB Stimulus, Induces the HIF Pathway. Cells.


D'Ignazio, Laura, Batie, Michael ORCID: 0000-0002-7508-6641 and Rocha, Sonia
(2018) TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway. CELLS, 7 (8). E102-.


Szenasi, Attila, Sivasudhan, Enakshi, Du, Hong, Zhang, Peizhuo, Huang, Jie, Zhang, Zhijun, Rocha, Sonia and Wang, Mu
(2023) Targeting SOD1 via RNAi with PEGylated graphene oxide nanoparticles in platinum-resistant ovarian cancer. CANCER GENE THERAPY, 30 (11). pp. 1554-1568.


Shakir, Dilem, Batie, Michael ORCID: 0000-0002-7508-6641 and Rocha, Sonia
(2021) Use of ChIP-qPCR to Study the Crosstalk Between HIF and NF-kappa B Signaling in Hypoxia and Normoxia. NF-(KAPPA)B TRANSCRIPTION FACTORS, 2366. pp. 255-265.


Frost, Julianty ORCID: 0000-0001-8209-2575, Rocha, Sonia ORCID: 0000-0002-2413-4981 and Ciulli, Alessio ORCID: 0000-0002-8654-1670
(2021) VHL ligand binding increases intracellular level of VHL. Journal of Biological Chemistry.


Frost, Julianty ORCID: 0000-0001-8209-2575, Rocha, Sonia and Ciulli, Alessio
(2021) Von Hippel-Lindau (VHL) small-molecule inhibitor binding increases stability and intracellular levels of VHL protein. JOURNAL OF BIOLOGICAL CHEMISTRY, 297 (2). 100910-.


Hill, Rhianna Mae, Fok, Matthew, Grundy, Gabrielle, Parsons, Jason Luke and Rocha, Sonia
(2023) The role of autophagy in hypoxia-induced radioresistance. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 189. 109951-.

This list was generated on Sun Feb 25 19:10:47 2024 GMT.