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Falconer, Adrian MD, Chan, Chun Ming, Gray, Joseph, Nagashima, Izuru, Holland, Robert A, Shimizu, Hiroki, Pickford, Andrew R, Rowan, Andrew D and Wilkinson, David J ORCID: 0000-0002-6262-3575
(2019)
Collagenolytic matrix metalloproteinases antagonize proteinase-activated receptor-2 activation, providing insights into extracellular matrix turnover.
JOURNAL OF BIOLOGICAL CHEMISTRY, 294 (26).
pp. 10266-10277.
Wilkinson, David J ORCID: 0000-0002-6262-3575, Habgood, Angela, Lamb, Heather K, Thompson, Paul, Hawkins, Alastair R, Désilets, Antoine, Leduc, Richard, Steinmetzer, Torsten, Hammami, Maya, Lee, Melody S et al (show 5 more authors)
(2017)
Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms.
Arthritis & Rheumatology, 69 (8).
pp. 1601-1611.
Wilkinson, David J ORCID: 0000-0002-6262-3575, Falconer, Adrian MD, Wright, Helen L ORCID: 0000-0003-0442-3134, Lin, Hua, Yamamoto, Kazuhiro ORCID: 0000-0002-8481-775X, Cheung, Kathleen, Charlton, Sarah H, Arques, Maria del Carmen, Janciauskiene, Sabina, Refaie, Ramsay et al (show 3 more authors)
(2022)
Matrix metalloproteinase-13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha-1 antitrypsin: Implications for osteoarthritis.
FEBS JOURNAL, 289 (1).
pp. 121-139.
Huesa, Carmen, Ortiz, Ana C, Dunning, Lynette, McGavin, Laura, Bennett, Louise, McIntosh, Kathryn, Crilly, Anne, Kurowska-Stolarska, Mariola, Plevin, Robin, van't Hof, Rob J et al (show 5 more authors)
(2016)
Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology.
ANNALS OF THE RHEUMATIC DISEASES, 75 (11).
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Hodgson, David, Rowan, Andrew D, Falciani, Francesco ORCID: 0000-0003-1432-2871 and Proctor, Carole J
(2019)
Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli.
PLOS COMPUTATIONAL BIOLOGY, 15 (1).
e1006685-.
Wilkinson, David J ORCID: 0000-0002-6262-3575, Desilets, Antoine, Lin, Hua, Charlton, Sarah, Arques, Maria del Carmen, Falconer, Adrian, Bullock, Craig, Hsu, Yu-Chen, Birchall, Kristian, Hawkins, Alastair et al (show 10 more authors)
(2017)
The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover.
SCIENTIFIC REPORTS, 7 (1).
16693-.