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Sarker, Debashis, Plummer, Ruth, Meyer, Tim, Sodergren, Mikael H, Basu, Bristi, Chee, Cheng Ean, Huang, Kai-Wen, Palmer, Daniel H ORCID: 0000-0002-7147-5703, Ting, Yuk, Evans, TR Jeff et al (show 26 more authors)
(2020)
MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-a, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial.
CLINICAL CANCER RESEARCH, 26 (15).
pp. 3936-3946.
Ghaneh, Paula, Hanson, Robert, Titman, Andrew, Lancaster, Gill, Plumpton, Catrin, Lloyd-Williams, Huw, Yeo, Seow Tien, Edwards, Rhiannon Tudor, Johnson, Colin, Abu Hilal, Mohammed et al (show 30 more authors)
(2018)
PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality <SUP>18</SUP>fluorine-2-fluoro-2-deoxy-D-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer.
HEALTH TECHNOLOGY ASSESSMENT, 22 (7).
1-+.
Verset, Gontran, Borbath, Ivan, Karwal, Mark, Verslype, Chris, Van Vlierberghe, Hans, Kardosh, Adel, Zagonel, Vittorina, Stal, Per, Sarker, Debashis, Palmer, Daniel H ORCID: 0000-0002-7147-5703 et al (show 16 more authors)
(2022)
Pembrolizumab Monotherapy for Previously Untreated Advanced Hepatocellular Carcinoma: Data from the Open-Label, Phase II KEYNOTE-224 Trial.
CLINICAL CANCER RESEARCH, 28 (12).
pp. 2547-2554.
Kristeleit, Rebecca ORCID: 0000-0003-3825-1326, Plummer, Ruth, Jones, Robert ORCID: 0000-0001-5608-001X, Carter, Louise, Blagden, Sarah ORCID: 0000-0001-8783-3491, Sarker, Debashis ORCID: 0000-0003-4814-8429, Arkenau, Tobias, Evans, Thomas R Jeffry, Danson, Sarah, Symeonides, Stefan N ORCID: 0000-0002-9892-9314 et al (show 4 more authors)
(2023)
A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer.
British journal of cancer, 129 (1).
pp. 38-45.
Jones, Robert ORCID: 0000-0001-5608-001X, Plummer, Ruth ORCID: 0000-0003-0107-1444, Moreno, Victor ORCID: 0000-0001-6099-4236, Carter, Louise ORCID: 0000-0002-9854-2304, Roda, Desamparados ORCID: 0000-0003-2657-9623, Garralda, Elena ORCID: 0000-0002-4412-7842, Kristeleit, Rebecca ORCID: 0000-0003-3825-1326, Sarker, Debashis ORCID: 0000-0003-4814-8429, Arkenau, Tobias ORCID: 0000-0002-2015-1549, Roxburgh, Patricia ORCID: 0000-0001-9869-591X et al (show 6 more authors)
(2023)
A Phase I/II Trial of Oral SRA737 (a Chk1 Inhibitor) Given in Combination with Low-Dose Gemcitabine in Patients with Advanced Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research, 29 (2).
pp. 331-340.
Kudo, Masatoshi, Finn, Richard S, Edeline, Julien, Cattan, Stephane, Ogasawara, Sadahisa, Palmer, Daniel H ORCID: 0000-0002-7147-5703, Verslype, Chris, Zagonel, Vittorina, Fartoux, Laetitia, Vogel, Arndt et al (show 11 more authors)
(2022)
Updated efficacy and safety of KEYNOTE-224: a phase II study of pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib.
EUROPEAN JOURNAL OF CANCER, 167.
pp. 1-12.
Hashimoto, Ayumi, Sarker, Debashis, Reebye, Vikash, Jarvis, Sheba, Sodergren, Mikael H, Kossenkov, Andrew, Sanseviero, Emilio, Raulf, Nina, Vasara, Jenni, Andrikakou, Pinelopi et al (show 21 more authors)
(2021)
Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer.
CLINICAL CANCER RESEARCH, 27 (21).
pp. 5961-5978.