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Tomlinison, Lauren, Lu, Zhen Qi, Bentley, Robert, Colley, Helen, Murdoch, Craig, Webb, Steven, Cross, Michael ORCID: 0000-0002-5533-1232, Copple, Ian ORCID: 0000-0003-4101-1913 and Sharma, Parveen ORCID: 0000-0002-5534-2417
(2019)
Attenuation of doxorubicin-induced cardiotoxicity in a human in vitro cardiac model by the induction of the NRF-2 pathway.
Biomedicine and Pharmacotherapy, 112.
108637-.
Lee, Shin-Haw, Hadipour-Lakmehsari, Sina, Kim, Da Hye, Di Paola, Michelle, Kuzmanov, Uros, Shah, Saumya, Lee, Joseph Jong-Hwan, Kislinger, Thomas, Sharma, Parveen ORCID: 0000-0002-5534-2417, Oudit, Gavin Y et al (show 1 more authors)
(2020)
Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium.
SCIENTIFIC DATA, 7 (1).
425-.
Kyffin, Jonathan A, Sharma, Parveen ORCID: 0000-0002-5534-2417, Leedale, Joseph ORCID: 0000-0001-9010-4126, Colley, Helen E, Murdoch, Craig, Harding, Amy L, Mistry, Pratibha and Webb, Steven D
(2019)
Characterisation of a functional rat hepatocyte spheroid model.
TOXICOLOGY IN VITRO, 55.
pp. 160-172.
Kilfoil, Peter, Feng, Shuyun Lily, Bassyouni, Asser, Lee, Tiffany, Leishman, Derek, Li, Dingzhou, MacEwan, David J ORCID: 0000-0002-2879-0935, Sharma, Parveen ORCID: 0000-0002-5534-2417, Watt, Eric D and Jenkinson, Stephen
(2021)
Characterization of a high throughput human stem cell cardiomyocyte assay to predict drug-induced changes in clinical electrocardiogram parameters.
European Journal of Pharmacology, 912.
p. 174584.
Cox, Christopher R, Lynch, Stephen, Goldring, Christopher and Sharma, Parveen ORCID: 0000-0002-5534-2417
(2020)
Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury.
FRONTIERS IN MEDICAL TECHNOLOGY, 2.
611913-.
Penman, Sophie L ORCID: 0000-0001-5326-1675, Sharma, Parveen, Aerts, Helene, Park, B Kevin ORCID: 0000-0001-8384-824X, Weaver, Richard J and Chadwick, Amy E ORCID: 0000-0002-7399-8655
(2019)
Differential toxic effects of bile acid mixtures in isolated mitochondria and physiologically relevant HepaRG cells.
TOXICOLOGY IN VITRO, 61.
104595-.
Bentley, Robert, Hardy, Lewis J, Scott, Laura J, Sharma, Parveen ORCID: 0000-0002-5534-2417, Philippou, Helen and Lip, Gregory YH
(2021)
Drugs in phase I and II clinical development for the prevention of stroke in patients with atrial fibrillation.
Expert Opinion on Investigational Drugs, 30 (10).
pp. 1057-1069.
Ramadan, Qasem and Sharma, Parveen ORCID: 0000-0002-5534-2417
(2021)
Editorial: Tissue Engineering for Drug Discovery and Personalized Medicine.
FRONTIERS IN MEDICAL TECHNOLOGY, 3.
663057-.
Cox, Christopher
(2023)
Evaluating the Role of Mitochondrial
Genetics in Adverse-Drug Reactions and the
Application of iPSC-Derived Hepatocytes
for Modelling Drug-Induced Liver Injury.
PhD thesis, University of Liverpool.
Blake, S, Proscia, C, Eleuteri, A ORCID: 0000-0003-0718-6672, Groves, D and Stables, RH ORCID: 0000-0002-9244-7015
(2020)
Identification of the high-risk patient in primary percutaneous coronary intervention: development and validation of a novel predictive index.
PhD thesis, University of Liverpool.
Kyffin, Jonathan A, Sharma, Parveen ORCID: 0000-0002-5534-2417, Leedale, Joseph ORCID: 0000-0001-9010-4126, Colley, Helen E, Murdoch, Craig, Mistry, Pratibha and Webb, Steven D
(2018)
Impact of cell types and culture methods on the functionality of <i>in vitro</i> liver systems - A review of cell systems for hepatotoxicity assessment.
TOXICOLOGY IN VITRO, 48.
pp. 262-275.
Kuzmanov, Uros, Wang, Erika Yan, Vanderlaan, Rachel, Kim, Da Hye, Lee, Shin-Haw, Hadipour-Lakmehsari, Sina, Guo, Hongbo, Zhao, Yimu, McFadden, Meghan, Sharma, Parveen ORCID: 0000-0002-5534-2417 et al (show 4 more authors)
(2020)
Mapping signalling perturbations in myocardial fibrosis via the integrative phosphoproteomic profiling of tissue from diverse sources.
Nature Biomedical Engineering, 4 (9).
pp. 889-900.
Roberts, James A, Rainbow, Richard D ORCID: 0000-0002-0532-1992 and Sharma, Parveen ORCID: 0000-0002-5534-2417
(2023)
Mitigation of Cardiovascular Disease and Toxicity through NRF2 Signalling.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (7).
6723-.
Alnaimi, Abrar
(2023)
Modulation of ion channels as cardioprotective targets in ischaemic injury.
PhD thesis, University of Liverpool.
Leedale, JA ORCID: 0000-0001-9010-4126, Kyffin, Jonathan, Harding, Amy, Colley, Helen, Murdoch, Craig, Sharma, Parveen ORCID: 0000-0002-5534-2417, Williams, Dominic ORCID: 0000-0002-0758-3152, Webb, Steven and Bearon, Rachel ORCID: 0000-0001-8461-0823
(2020)
Multiscale modelling of drug transport and metabolism in liver spheroids.
Interface Focus, 10 (2).
20190041-.
Bentley, Robert, Logantha, Sunil Jit RJ, Sharma, Parveen ORCID: 0000-0002-5534-2417, Rainbow, Richard R and Lip, Gregory YH
(2021)
Pathophysiological insights into atrial fibrillation: revisiting the electrophysiological substrate, anatomical substrate, and possible insights from proteomics.
CARDIOVASCULAR RESEARCH, 117 (3).
E41-E45.
Kyffin, Jonathan A, Cox, Christopher R, Leedale, Joseph ORCID: 0000-0001-9010-4126, Colley, Helen E, Murdoch, Craig, Mistry, Pratibha, Webb, Steven D and Sharma, Parveen ORCID: 0000-0002-5534-2417
(2019)
Preparation of Primary Rat Hepatocyte Spheroids Utilizing the Liquid-Overlay Technique.
Current protocols in toxicology, 81 (1).
e87-e87.
Lee, Shin-Haw, Hadipour-Lakmehsari, Sina, Murthy, Harsha R, Gibb, Natalie, Miyake, Tetsuaki, Teng, Allen CT, Cosme, Jake, Yu, Jessica C, Moon, Mark, Lim, SangHyun et al (show 9 more authors)
(2020)
REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.
NATURE COMMUNICATIONS, 11 (1).
965-.
Brennan, Sean, Esposito, Simona, Abdelaziz, Muhammad IM, Martin, Christopher AA, Makwana, Samir, Sims, Mark WW, Squire, Iain BB, Sharma, Parveen ORCID: 0000-0002-5534-2417, Chadwick, Amy EE ORCID: 0000-0002-7399-8655 and Rainbow, Richard D ORCID: 0000-0002-0532-1992
(2022)
Selective protein kinase C inhibition switches time-dependent glucose cardiotoxicity to cardioprotection.
FRONTIERS IN CARDIOVASCULAR MEDICINE, 9.
997013-.
Brennan, Sean ORCID: 0000-0002-7604-9842, Alnaimi, Abrar IM, Mcguinness, Lauren R, Abdelaziz, Muhammad IM, Mckenzie, Robert A, Draycott, Sophie, Whitmore, Jacob, Sharma, Parveen ORCID: 0000-0002-5534-2417 and Rainbow, Richard D ORCID: 0000-0002-0532-1992
(2023)
Slowly activating voltage-gated potassium current potentiation by ML277 is a novel cardioprotective intervention.
PNAS NEXUS, 2 (5).
pgad156-.
Lynch, Stephen, Pridgeon, Chris S, Duckworth, Carrie A ORCID: 0000-0001-9992-7540, Sharma, Parveen ORCID: 0000-0002-5534-2417, Park, B Kevin ORCID: 0000-0001-8384-824X and Goldring, Chris EP
(2019)
Stem cell models as an <i>in vitro</i> model for predictive toxicology.
BIOCHEMICAL JOURNAL, 476 (7).
pp. 1149-1158.
Penman, Sophie ORCID: 0000-0001-5326-1675
(2020)
Towards Improved Models for the
Study of the Multi-mechanistic
Toxicity of Drug-induced Liver
Injury.
PhD thesis, University of Liverpool.
Arasti Rezola, M
(2019)
The adipocyte plasma membrane proteome and its role in
drug-induced metabolic toxicity.
PhD thesis, University of Liverpool.
Leedale, JA ORCID: 0000-0001-9010-4126, Sharkey, Kieran ORCID: 0000-0002-7210-9246, Colley, Helen, Norton, Aine, Peeney, David, Mason, Chantelle, Sathish, Jean, Murdoch, Craig, Sharma, Parveen ORCID: 0000-0002-5534-2417 and Webb, Steven
(2018)
A combined in vitro/in silico approach to identifying off-target receptor toxicity.
iScience, 4.
84 - 96.
Tomlinson, Lauren, Hyndman, Lauren, Firman, James W, Bentley, Robert, Kyffin, Jonathan A, Webb, Steven D, McGinty, Sean and Sharma, Parveen ORCID: 0000-0002-5534-2417
(2019)
<i>In vitro</i> Liver Zonation of Primary Rat Hepatocytes.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 7.
17-.