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Number of items: 44.


Hobson, James J ORCID: 0000-0003-2551-1774, Curley, Paul ORCID: 0000-0003-4596-2708, Savage, Alison C ORCID: 0000-0002-5312-9946, Al-khouja, Amer, Siccardi, Marco ORCID: 0000-0002-3539-7867, Flexner, Charles, Meyers, Caren Freel, Owen, Andrew ORCID: 0000-0002-9819-7651 and Rannard, Steve P ORCID: 0000-0002-6946-1097
(2019) Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations. NANOSCALE ADVANCES, 1 (11). 4301 - 4307.


Chan, CY
(2018) Assessment of degradation rate constants for quantitative predictions of drug-drug interactions arising from CYP450 drug metabolising enzymes. PhD thesis, University of Liverpool.


Neary, MG
(2018) Assessment of the inter-individual variation observed between patients receiving HIV antiretroviral therapy. PhD thesis, University of Liverpool.


Olagunju, Adeniyi, Bolaji, Oluseye, Amara, Alieu, Waitt, Catriona, Else, Laura, Adejuyigbe, Ebunoluwa, Siccardi, Marco, Back, David, Khoo, Saye and Owen, Andrew
(2015) Breast milk pharmacokinetics of efavirenz and breastfed infants' exposure in genetically-defined subgroups of mother-infant pairs: an observational study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.


Neary, MG ORCID: 0000-0002-4960-2139, Chappell, Catherine, Scarsi, Kimberly, Nakalema, Shadia, Matovu, Joshua, Achilles, Sharon, Chen, Beatrice, Siccardi, Marco ORCID: 0000-0002-3539-7867, Owen, Andrew ORCID: 0000-0002-9819-7651 and Lamorde, Mohammed
(2018) CYP2B6 variants alter etonogestrel pharmacokinetics when combined with efavirenz. In: CROI, 2018-03-05 - 2018-03-08, Boston, MA, USA.


Stader, Felix, Courlet, Perrine, Kinvig, Hannah ORCID: 0000-0002-0061-1683, Penny, Melissa A, Decosterd, Laurent A, Battegay, Manuel, Siccardi, Marco ORCID: 0000-0002-3539-7867 and Marzolini, Catia
(2021) Clinical Data Combined With Modeling and Simulation Indicate Unchanged Drug-Drug Interaction Magnitudes in the Elderly. CLINICAL PHARMACOLOGY & THERAPEUTICS, 109 (2). 471 - 484.


Cottura, Nicolas ORCID: 0000-0003-3083-2249, Howarth, Alice, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2020) The Current Landscape of Novel Formulations and the Role of Mathematical Modeling in Their Development. JOURNAL OF CLINICAL PHARMACOLOGY, 60. S77 - S97.


Chan, Christina YS, Roberts, Owain, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Siccardi, Marco ORCID: 0000-0002-3539-7867, Almond, Lisa and Owen, Andrew ORCID: 0000-0002-9819-7651
(2018) Derivation of CYP3A4 and CYP2B6 degradation rate constants in primary human hepatocytes: A siRNA-silencing-based approach. DRUG METABOLISM AND PHARMACOKINETICS, 33 (4). 179 - 187.


Curley, Paul ORCID: 0000-0003-4596-2708, Siccardi, Marco ORCID: 0000-0002-3539-7867, Moss, Darren M and Owen, Andrew ORCID: 0000-0002-9819-7651
(2016) Development and validation of an LC-MS/MS assay for the quantification of efavirenz in different biological matrices. BIOANALYSIS, 8 (20). 2125 - 2134.


Olagunju, Adeniyi ORCID: 0000-0002-6588-5749, Bolaji, Oluseye O, Amara, Alieu ORCID: 0000-0002-1137-2948, Waitt, Catriona ORCID: 0000-0003-0134-5855, Else, Laura, Soyinka, Julius, Adeagbo, Babatunde, Adejuyigbe, Ebunoluwa, Siccardi, Marco ORCID: 0000-0002-3539-7867, Back, David
et al (show 2 more authors) (2015) Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70 (2). 555 - 561.


Cirrincione, Lauren R, Penchala, Sujan Dilly, Scarsi, Kimberly K, Podany, Anthony T, Winchester, Lee C, Back, David J, Khoo, Saye H, Fletcher, Courtney V, Siccardi, Marco ORCID: 0000-0002-3539-7867 and Else, Laura J
(2018) Development, validation and utilization of a highly sensitive LC-MS/MS method for quantification of levonorgestrel released from a subdermal implant in human plasma. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1084. 106 - 112.


Hodge, Catherine, Marra, Fiona ORCID: 0000-0003-1326-1149, Marzolini, Catia, Boyle, Alison, Gibbons, Sara, Siccardi, Marco ORCID: 0000-0002-3539-7867, Burger, David, Back, David and Khoo, Saye
(2020) Drug interactions: a review of the unseen danger of experimental COVID-19 therapies. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 75 (12). 3417 - 3424.


Town, Adam, Gurjar, Rohan, Giardiello, Marco ORCID: 0000-0003-0560-4711, Briggs, Michael, Akhtar, Riaz ORCID: 0000-0002-7963-6874, Siccardi, Marco ORCID: 0000-0002-3539-7867 and McDonald, Tom ORCID: 0000-0002-9273-9173
(2017) Dual-stimuli responsive injectable nanogel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs. .


Curley, Paul ORCID: 0000-0003-4596-2708, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Moss, Darren M, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Letendre, Scott, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2017) Efavirenz Is Predicted To Accumulate in Brain Tissue: an In Silico, In Vitro, and In Vivo Investigation. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (1).


Adegbola, Adebanjo, Abutaima, Rana, Olagunju, Adeniyi ORCID: 0000-0002-6588-5749, Ijarotimi, Omotade, Siccardi, Marco ORCID: 0000-0002-3539-7867, Owen, Andrew ORCID: 0000-0002-9819-7651, Soyinka, Julius and Bolaji, Oluseye
(2018) Effect of Pregnancy on the Pharmacokinetic Interaction between Efavirenz and Lumefantrine in HIV-Malaria Coinfection. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62 (10).


Neary, Megan ORCID: 0000-0002-4960-2139, Chappell, Catherine A, Scarsi, Kimberly K, Nakalema, Shadia, Matovu, Joshua, Achilles, Sharon L, Chen, Beatrice A, Siccardi, Marco ORCID: 0000-0002-3539-7867, Owen, Andrew ORCID: 0000-0002-9819-7651 and Lamorde, Mohammed
(2019) Effect of patient genetics on etonogestrel pharmacokinetics when combined with efavirenz or nevirapine ART. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 74 (10). 3003 - 3010.


Gini, Joshua, Olagunju, Adeniyi ORCID: 0000-0002-6588-5749, Dickinson, Laura ORCID: 0000-0001-5557-9396, Waitt, Catriona ORCID: 0000-0003-0134-5855, Neary, Megan ORCID: 0000-0002-4960-2139, Else, Laura J, Siccardi, Marco ORCID: 0000-0002-3539-7867 and Khoo, Saye
(2019) Impact of pharmacogenetics and pregnancy on tenofovir and emtricitabine pharmacokinetics. PHARMACOGENOMICS, 20 (4). 217 - 224.


Savage, Alison C ORCID: 0000-0002-5312-9946, Tatham, Lee M ORCID: 0000-0001-9448-8876, Siccardi, Marco ORCID: 0000-0002-3539-7867, Scott, Trevor, Vourvahis, Manoli, Clark, Andrew, Rannard, Steve P ORCID: 0000-0002-6946-1097 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2019) Improving maraviroc oral bioavailability by formation of solid drug nanoparticles. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 138. 30 - 36.


Curley, Paul, Giardiello, Marco ORCID: 0000-0003-0560-4711, Liptrott, Neill J, Dickens, David ORCID: 0000-0001-8295-0752, Moss, Darren M, Hobson, James J ORCID: 0000-0003-2551-1774, Savage, Alison C, McDonald, Tom O, Siccardi, Marco, Rannard, Steve
et al (show 1 more authors) (2017) In vitro characterisation of solid drug nanoparticle compositions of efavirenz in a brain endothelium cell line. Journal of Interdisciplinary Nanomedicine, 2 (3). 157 - 169.


Chan, Christina, Martin, Philip, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Siccardi, Marco ORCID: 0000-0002-3539-7867, Almond, Lisa and Owen, Andrew ORCID: 0000-0002-9819-7651
(2017) Incompatibility of chemical protein synthesis inhibitors with accurate measurement of extended protein degradation rates. PHARMACOLOGY RESEARCH & PERSPECTIVES, 5 (5).


Roberts, Owain, Khoo, Saye, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2017) Interaction of Rifampin and Darunavir-Ritonavir or Darunavir-Cobicistat In Vitro. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (5).


Gini, J
(2018) Investigating the Effectiveness of Antiretroviral Therapy in sub-Saharan Africa. Doctor of Philosophy thesis, University of Liverpool.


Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Flexner, Charles, Chiong, Justin, Owen, Andrew ORCID: 0000-0002-9819-7651, Donnelly, Ryan F, Larraneta, Eneko and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2019) Modelling the intradermal delivery of microneedle array patches for long-acting antiretrovirals using PBPK. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 144. 101 - 109.


Marzolini, Catia, Rajoli, Rajith ORCID: 0000-0002-6015-5712, Battegay, Manuel, Elzi, Luigia, Back, David and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2017) Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes. CLINICAL PHARMACOKINETICS, 56 (4). 409 - 420.


Stader, Felix, Kinvig, Hannah ORCID: 0000-0002-0061-1683, Penny, Melissa A, Battegay, Manuel, Siccardi, Marco ORCID: 0000-0002-3539-7867 and Marzolini, Catia
(2020) Physiologically Based Pharmacokinetic Modelling to Identify Pharmacokinetic Parameters Driving Drug Exposure Changes in the Elderly. CLINICAL PHARMACOKINETICS, 59 (3). 383 - 401.


Roberts, Owain, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Back, David J, Owen, Andrew ORCID: 0000-0002-9819-7651, Darin, Kristin M, Fletcher, Courtney V, Lamorde, Mohammed, Scarsi, Kimberly K and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2018) Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug–drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART. Journal of Antimicrobial Chemotherapy, 73 (4). 1004 - 1012.


Saeheng, Teerachat, Na-Bangchang, Kesara, Siccardi, Marco ORCID: 0000-0002-3539-7867, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712 and Karbwang, Juntra
(2020) Physiologically-Based Pharmacokinetic Modeling for Optimal Dosage Prediction of Quinine Coadministered With Ritonavir-Boosted Lopinavir. CLINICAL PHARMACOLOGY & THERAPEUTICS, 107 (5). 1209 - 1220.


Olagunju, A ORCID: 0000-0002-6588-5749, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Atoyebi, Shakir Adeyinka, Khoo, Saye, Owen, Andrew and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2018) Physiologically-based pharmacokinetic modelling of infant exposure to efavirenz through breastfeeding. AAS Open Research, 1 (16).


Olagunju, Adeniyi, Rajoli, Rajith, Atoyebi, Shakir, Khoo, Saye, Owen, Andrew and Siccardi, Marco
(2018) Physiologically-based pharmacokinetic modelling of infant exposure to efavirenz through breastfeeding.


Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Curley, Paul ORCID: 0000-0003-4596-2708, Chiong, Justin ORCID: 0000-0001-8063-6399, Back, David, Flexner, Charles, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2019) Predicting Drug-Drug Interactions Between Rifampicin and Long-Acting Cabotegravir and Rilpivirine Using Physiologically Based Pharmacokinetic Modeling. JOURNAL OF INFECTIOUS DISEASES, 219 (11). 1735 - 1742.


Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Demkovich, Zach R, Flexner, Charles, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2020) Predicting pharmacokinetics of a tenofovir alafenamide subcutaneous implant using PBPK modelling. Antimicrobial Agents and Chemotherapy.


Bunglawala, Fazila, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Mirochnick, Mark, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2020) Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 75 (3). 640 - 647.


Marra, Fiona ORCID: 0000-0003-1326-1149, Smolders, Elise J, El-Sherif, Omar, Boyle, Alison, Davidson, Katherine, Sommerville, Andrew J, Marzolini, Catia, Siccardi, Marco ORCID: 0000-0002-3539-7867, Burger, David, Gibbons, Sara
et al (show 2 more authors) (2021) Recommendations for Dosing of Repurposed COVID-19 Medications in Patients with Renal and Hepatic Impairment. DRUGS IN R&D, 21 (1). 9 - 27.


Stader, Felix, Siccardi, Marco ORCID: 0000-0002-3539-7867, Battegay, Manuel, Kinvig, Hannah ORCID: 0000-0002-0061-1683, Penny, Melissa A and Marzolini, Catia
(2019) Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes. CLINICAL PHARMACOKINETICS, 58 (4). 483 - 501.


Hobson, James ORCID: 0000-0003-2551-1774, Al-Khouja, Amer, Curley, Paul ORCID: 0000-0003-4596-2708, Meyers, David, Flexner, Charles, Siccardi, Marco ORCID: 0000-0002-3539-7867, Owen, Andrew ORCID: 0000-0002-9819-7651, Freel Meyers, Caren and Rannard, SP ORCID: 0000-0002-6946-1097
(2019) Semi-solid prodrug nanoparticles for long-acting delivery of water-soluble antiretroviral drugs within combination HIV therapies. Nature Communications, 10.


Moss, Darren M, Domanico, Paul, Watkins, Melynda, Park, Seonghee, Randolph, Ryan, Wring, Steve, Rajoli, Rajith Kumar Reddy ORCID: 0000-0002-6015-5712, Hobson, James ORCID: 0000-0003-2551-1774, Rannard, Steve ORCID: 0000-0002-6946-1097, Siccardi, Marco ORCID: 0000-0002-3539-7867
et al (show 1 more authors) (2017) Simulating Intestinal Transporter and Enzyme Activity in a Physiologically Based Pharmacokinetic Model for Tenofovir Disoproxil Fumarate. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (7).


Dickinson, Laura ORCID: 0000-0001-5557-9396, Winston, Alan, Boffito, Marta, Khoo, Saye, Back, David and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2016) Simulation of the impact of rifampicin on once-daily darunavir/ritonavir pharmacokinetics and dose adjustment strategies: a population pharmacokinetic approach. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 71 (4). 1041 - 1045.


Tatham, Lee M ORCID: 0000-0001-9448-8876, Savage, Alison C ORCID: 0000-0002-5312-9946, Dwyer, Andrew, Siccardi, Marco ORCID: 0000-0002-3539-7867, Scott, Trevor, Vourvahis, Manoli, Clark, Andrew, Rannard, Steven P ORCID: 0000-0002-6946-1097 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2019) Towards a Maraviroc long-acting injectable nanoformulation. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 138. 92 - 98.


Siccardi, Marco ORCID: 0000-0002-3539-7867, Martin, Phillip, Smith, Darren ORCID: 0000-0003-4925-467X, Curley, Paul, McDonald, Tom, Giardiello, Marco ORCID: 0000-0003-0560-4711, Liptrott, Neill, Rannard, Steve and Owen, Andrew ORCID: 0000-0002-9819-7651
(2016) Towards a rational design of solid drug nanoparticles with optimised pharmacological properties. Journal of interdisciplinary nanomedicine, 1 (3). 110 - 123.


Siccardi, Marco ORCID: 0000-0002-3539-7867, Dickinson, Laura ORCID: 0000-0001-5557-9396 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2016) Validation of Computational Approaches for Antiretroviral Dose Optimization (vol 60, pg 3838, 2016). ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (1).


Siccardi, Marco ORCID: 0000-0002-3539-7867, Schapiro, Jonathan, Di Perri, Giovanni and Back, David J
(2020) The challenging pathway towards the identification of SARS-CoV-2/COVID-19 therapeutics. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 75 (9). 2381 - 2383.


Stader, Felix, Penny, Melissa A, Siccardi, Marco ORCID: 0000-0002-3539-7867 and Marzolini, Catia
(2019) A comprehensive framework for physiologically based pharmacokinetic modelling in Matlab®. CPT: pharmacometrics & systems pharmacology.


Siccardi, Marco ORCID: 0000-0002-3539-7867, Rannard, Steve ORCID: 0000-0002-6946-1097 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2018) The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation. Advanced Drug Delivery Reviews, 131. 116 - 121.


Henrique Silva, Adny, Lima Jr, Enio, Vasquez Mansilla, Marcelo, Zysler, Roberto Daniel, Mojica Pisciotti, Mary Luz, Locatelli, Claudriana, Kumar Reddy Rajoli, Rajith, Owen, Andrew ORCID: 0000-0002-9819-7651, Creczynski-Pasa, Tânia Beatriz and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2017) A physiologically based pharmacokinetic model to predict the superparamagnetic iron oxide nanoparticles (SPIONs) accumulation in vivo. European Journal of Nanomedicine, 9 (2).

This list was generated on Mon May 3 20:02:10 2021 BST.