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Kamalian, Laleh, Douglas, Oisin, Jolly, Carol E, Snoeys, Jan, Simic, Damir, Monshouwer, Mario, Williams, Dominic P ORCID: 0000-0002-0758-3152, Park, B Kevin ORCID: 0000-0001-8384-824X and Chadwick, Amy E ORCID: 0000-0002-7399-8655
(2019)
Acute Metabolic Switch Assay Using Glucose/Galactose Medium in HepaRG Cells to Detect Mitochondrial Toxicity.
Current protocols in toxicology, 80 (01).
e76-.
Alhilali, Khetam Ali, Al-Attar, Zaid, Gibson, Andrew, Tailor, Arun ORCID: 0000-0002-9698-3480, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Monshouwer, Mario, Snoeys, Jan, Park, B Kevin ORCID: 0000-0001-8384-824X and Naisbitt, Dean J
(2019)
Characterization of Healthy Donor-Derived T-Cell Responses Specific to Telaprevir Diastereomers.
TOXICOLOGICAL SCIENCES, 168 (2).
pp. 597-609.
Bell, Catherine C, Hendriks, Delilah FG, Moro, Sabrina ML, Ellis, Ewa, Walsh, Joanne, Renblom, Anna, Fredriksson Puigvert, Lisa, Dankers, Anita CA, Jacobs, Frank, Snoeys, Jan et al (show 9 more authors)
(2016)
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.
Scientific Reports, 6 (1).
25187-.
Bell, Catherine C, Dankers, Anita CA, Lauschke, Volker M, Sison-Young, Rowena, Jenkins, Roz, Rowe, Cliff, Goldring, Chris E, Park, Kevin ORCID: 0000-0001-8384-824X, Regan, Sophie L, Walker, Tracy et al (show 12 more authors)
(2018)
Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study.
TOXICOLOGICAL SCIENCES, 162 (2).
pp. 655-666.
Bell, Catherine, Dankers, Anita, Lauschke, Volker, Sison-Young, Rowena, Jenkins, Rosalind, Rowe, Cliff, Goldring, Chris, Park, Brian ORCID: 0000-0001-8384-824X, Regan, Sophie, Walker, Tracy et al (show 12 more authors)
(2018)
Comparison of hepatic 2D sandwich cultures and 3D spheroids for long-term toxicity applications: A multi-center study.
Toxicological Sciences.
Thomson, Paul J ORCID: 0000-0001-5431-0459, Kafu, Laila, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Snoeys, Jan, De Bondt, An, De Maeyer, Dries, Wils, Hans, Leclercq, Laurent, Vinken, Petra and Naisbitt, Dean J
(2021)
Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat.
ALLERGY, 76 (6).
pp. 1825-1835.
Dragovic, Sanja, Vermeulen, Nico PE, Gerets, Helga H, Hewitt, Philip G, Ingelman-Sundberg, Magnus, Park, B Kevin ORCID: 0000-0001-8384-824X, Juhila, Satu, Snoeys, Jan and Weaver, Richard J
(2016)
Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man.
ARCHIVES OF TOXICOLOGY, 90 (12).
pp. 2979-3003.
Weaver, Richard J, Blomme, Eric A, Chadwick, Amy E ORCID: 0000-0002-7399-8655, Copple, Ian M ORCID: 0000-0003-4101-1913, Gerets, Helga HJ, Goldring, Christopher E, Guillouzo, Andre, Hewitt, Philip G, Ingelman-Sundberg, Magnus, Jensen, Klaus Gjervig et al (show 12 more authors)
(2020)
Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models.
NATURE REVIEWS DRUG DISCOVERY, 19 (2).
pp. 131-148.
Kamalian, Laleh, Chadwick, Amy ORCID: 0000-0002-7399-8655, Bayliss, Mark, French, Neil ORCID: 0000-0002-9376-3482, Monshouwer, Mario, Snoeys, Jan and Park, B Kevin ORCID: 0000-0001-8384-824X
(2015)
The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death.
Toxicology in Vitro, 29 (4).
pp. 732-740.
Kamalian, Laleh, Douglas, Oisin, Jolly, Carol E, Snoeys, Jan, Simic, Damir, Monshouwer, Mario, Williams, Dominic P ORCID: 0000-0002-0758-3152, Park, B Kevin ORCID: 0000-0001-8384-824X and Chadwick, Amy E ORCID: 0000-0002-7399-8655
(2018)
The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity.
TOXICOLOGY IN VITRO, 53.
pp. 136-147.
Jolly, Carol E, Douglas, Oisin, Kamalian, Laleh, Jenkins, Rosalind E, Beckett, Alison J ORCID: 0000-0001-8377-325X, Penman, Sophie L ORCID: 0000-0001-5326-1675, Williams, Dominic P ORCID: 0000-0002-0758-3152, Monshouwer, Mario, Simic, Damir, Snoeys, Jan et al (show 2 more authors)
(2020)
The utility of a differentiated preclinical liver model, HepaRG cells, in investigating delayed toxicity via inhibition of mitochondrial-replication induced by fialuridine.
Toxicology and applied pharmacology, 403.
115163-.