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Number of items: 23.


Yedida, Govindaraju, Milani, Mateus, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2019) Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis. CELL DEATH & DISEASE, 10 (7). 521-.


Butterworth, Michael, Pettitt, Andrew, Varadarajan, Shankar ORCID: 0000-0002-8827-6567 and Cohen, Gerald M
(2016) BH3 profiling and a toolkit of BH3-mimetic drugs predict anti-apoptotic dependence of cancer cells. BRITISH JOURNAL OF CANCER, 114 (6). pp. 638-641.


Greaves, Georgia, Milani, Mateus, Butterworth, Michael, Carter, Rachel J, Byrne, Dominic P, Eyers, Patrick A ORCID: 0000-0002-9220-2966, Luo, Xu, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2019) BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-X-L. CELL DEATH AND DIFFERENTIATION, 26 (6). pp. 1037-1047.


Milani, Mateus, Beckett, Alison J ORCID: 0000-0001-8377-325X, Al-Zebeeby, Aoula, Luo, Xu, Prior, Ian A ORCID: 0000-0002-4055-5161, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2019) DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis. Cell death discovery, 5 (1). p. 117.


Milani, Mateus, Byrne, Dominic P, Greaves, Georgia, Butterworth, Michael, Cohen, Gerald M, Eyers, Patrick A ORCID: 0000-0002-9220-2966 and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2018) DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis. Cell Death and Disease, 8 (1). e2552-.


Yedida, Govinda
(2020) Dihydroorotate dehydrogenase regulates ER membrane reorganisation and cell death in cancer. PhD thesis, University of Liverpool.


Milani, Mateus, Cohen, Gerald and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2018) ER shaping proteins regulate mitochondrial fission, outer membrane permeabilization and apoptosis.


Basabrain, Ammar
(2023) Evaluation of CIP2A and BCL-XL as predictive biomarkers in Chronic Myeloid Leukaemia & Head and Neck Cancer. PhD thesis, University of Liverpool.


Alotibi, Ahoud
(2021) Exploring the Therapeutic Potential and Molecular Mechanisms of Targeting mTOR Kinases in Cancer. PhD thesis, University of Liverpool.


Carter, Rachel J, Milani, Mateus, Butterworth, Michael, Alotibi, Ahoud, Harper, Nicholas, Yedida, Govindaraju, Greaves, Georgia, Al-Zebeeby, Aoula, Jorgensen, Andrea L ORCID: 0000-0002-6977-9337, Schache, Andrew G ORCID: 0000-0001-9466-6038
et al (show 7 more authors) (2019) Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck. Cell Death and Disease, 10 (12). 912-.


Milani, M
(2019) Exploring the therapeutic potential and cellular mechanisms of BH3 mimetic-mediated apoptosis in cancer. PhD thesis, University of Liverpool.


Alsubhi, Mohammed
(2023) Functional Characterisation of FABP5/ TKT/ FASN Axis in Prostate Cancer. PhD thesis, University of Liverpool.


Baedyananda, Fern, Chaiwongkot, Arkom, Varadarajan, Shankar ORCID: 0000-0002-8827-6567 and Bhattarakosol, Parvapan
(2021) HPV16 E1 dysregulated cellular genes involved in cell proliferation and host DNA damage: A possible role in cervical carcinogenesis. PLOS ONE, 16 (12). e0260841-.


Varadarajan, Shankar ORCID: 0000-0002-8827-6567, Poornima, Paramasivan, Milani, Mateus, Gowda, Krishne, Amin, Shantu, Wang, Hong-Gang and Cohen, Gerry
(2015) Maritoclax and Dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and -independent manner. Oncotarget, 6 (14). pp. 12668-12681.


Carter, Rachel J, Milani, Mateus, Beckett, Alison J ORCID: 0000-0001-8377-325X, Liu, Shiyu, Prior, Ian A ORCID: 0000-0002-4055-5161, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2022) Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis. CELL DEATH & DISEASE, 13 (5). 436-.


Zhuang, Jack ORCID: 0000-0003-3245-0789, Luckett, Teifion, Cheng, Xiang, Oates, Melanie, Varadarajan, Shankar ORCID: 0000-0002-8827-6567 and Pettitt, Andrew
(2020) Resistance to venetoclax-induced apoptosis of CLL cells due to CD40 stimulation can be reversed by BCL-XL inhibition. .


Baedyananda, Fern, Sasivimolrattana, Thanayod, Chaiwongkot, Arkom, Varadarajan, Shankar ORCID: 0000-0002-8827-6567 and Bhattarakosol, Parvapan
(2022) Role of HPV16 E1 in cervical carcinogenesis. PhD thesis, University of Liverpool.


Henz, Kristina, Al-Zebeeby, Aoula, Basoglu, Marion, Fulda, Simone, Cohen, Gerald M, Varadarajan, Shankar ORCID: 0000-0002-8827-6567 and Vogler, Meike
(2019) Selective BH3-mimetics targeting BCL-2, BCL-X<sub>L</sub> or MCL-1 induce severe mitochondrial perturbations. BIOLOGICAL CHEMISTRY, 400 (2). pp. 181-185.


Al-Zebeeby, Aoula, Vogler, Meike, Milani, Mateus, Richards, Caitlin, Alotibi, Ahoud, Greaves, Georgia, Dyer, Martin JS, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2019) Targeting Intermediary Metabolism Enhances The Efficacy Of BH3 Mimetic Therapy In Haematological Malignancies. Haematologica: the hematology journal, 104 (5). pp. 1016-1025.


Al-Zebeeby, Aoula, Vogler, Meike, Milani, Mateus, Richards, Caitlin, Alotibi, Ahoud, Greaves, Georgia, Dyer, Martin JS, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2018) Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in haematological malignancies. Haematologica: the hematology journal.


Al-Zebeeby, AE
(2019) Targeting the glutamine metabolic pathway enhances sensitivity to BH3 mimetics in different malignancies. PhD thesis, University of Liverpool.


Greaves, GJ
(2019) The complex regulatory mechanisms of the BCL-2 family of proteins in cancer. PhD thesis, University of Liverpool.


Varadarajan, Shankar ORCID: 0000-0002-8827-6567, Breda, Carlo, Smalley, Joshua, Butterworth, Michael, Farrow, Stuart, Giorgini, Flaviano and Cohen, Gerry
(2015) The transrepression arm of glucocorticoid receptor signaling is protective in mutant huntingtin-mediated neurodegeneration. Cell Death and Differentiation, 22 (8). pp. 1388-1396.

This list was generated on Sat Feb 3 05:15:20 2024 GMT.