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Number of items: 17.


Hong, W David, Benayoud, Farid, Nixon, Gemma L, Ford, Louise, Johnston, Kelly L, Clare, Rachel H, Cassidy, Andrew, Cook, Darren AN, Siu, Amy, Shiotani, Motohiro
et al (show 24 more authors) (2019) AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116 (4). 1414 - 1419.


Turner, Joseph D, Sharma, Raman, Al Jayoussi, Ghaith, Tyrer, Hayley E, Gamble, Joanne ORCID: 0000-0001-7302-3412, Hayward, Laura, Priestley, Richard S, Murphy, Emma A, Davies, Jill, Waterhouse, David
et al (show 10 more authors) (2017) Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114 (45). E9712 - E9721.


Camarda, Grazia, Jirawatcharadech, Piyaporn, Priestley, Richard S, Saif, Ahmed, March, Sandra, Wong, Michael HL, Leung, Suet, Miller, Alex B, Baker, David A, Alano, Pietro
et al (show 5 more authors) (2019) Antimalarial activity of primaquine operates via a two-step biochemical relay. NATURE COMMUNICATIONS, 10.


Ismail, Hanafy M, Barton, Victoria E, Panchana, Matthew, Charoensutthivarakul, Sitthivut, Biagini, Giancarlo A ORCID: 0000-0001-6356-6595, Ward, Stephen A and O'Neill, Paul M ORCID: 0000-0003-4338-0317
(2016) A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile. Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 128 (22). 6511 - 6515.


Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Pertinez, Henry, Arshad, Usman ORCID: 0000-0003-1586-1885, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Valentijn, Anthony
et al (show 13 more authors) (2020) Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY.


Rajoli, Rajith Kr, Pertinez, Henry, Arshad, Usman, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J, Valentijn, Anthony
et al (show 13 more authors) (2020) Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis. medRxiv : the preprint server for health sciences.


Copple, Ian M ORCID: 0000-0003-4101-1913, Mercer, Amy E, Firman, James, Donegan, Gail, Herpers, Bram, Wong, Michael HL, Chadwick, James, Bringela, Andreia D, Cristiano, Maria LS, van de Water, Bob
et al (show 3 more authors) (2012) Examination of the Cytotoxic and Embryotoxic Potential and Underlying Mechanisms of Next-Generation Synthetic Trioxolane and Tetraoxane Antimalarials. MOLECULAR MEDICINE, 18 (7). 1045 - 1055.


Johnston, Kelly L, Cook, Darren AN, Berry, Neil G ORCID: 0000-0003-1928-0738, Hong, W David, Clare, Rachel H, Goddard, Megan, Ford, Louise, Nixon, Gemma L, O'Neill, Paul M ORCID: 0000-0003-4338-0317, Ward, Stephen A
et al (show 1 more authors) (2017) Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library. SCIENCE ADVANCES, 3 (09).


Clare, Rachel H, Bardelle, Catherine, Harper, Paul, Hong, W David, Borjesson, Ulf, Johnston, Kelly L, Collier, Matthew, Myhill, Laura, Cassidy, Andrew, Plant, Darren
et al (show 21 more authors) (2019) Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides. NATURE COMMUNICATIONS, 10.


O' Neill, Paul M, Sabbani, Sunil, Nixon, Gemma L, Schnaderbeck, Matthew, Roberts, Natalie L, Shore, Emma R, Riley, Christopher, Murphy, Ben, McGillan, Paul, Ward, Stephen A
et al (show 2 more authors) (2016) Optimisation of the synthesis of second generation 1,2,4,5 tetraoxane antimalarials. TETRAHEDRON, 72 (40). 6118 - 6126.


Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Rajoli, Rajith Kr ORCID: 0000-0002-6015-5712, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Valentijn, Anthony
et al (show 12 more authors) (2020) Prioritisation of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics. Clinical pharmacology and therapeutics.


Aljayyoussi, Ghaith, Tyrer, Hayley E, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas, Waterhouse, David, Davies, Jill, Gamble, Joanne ORCID: 0000-0001-7302-3412, Metugene, Haelly, Cook, Darren AN
et al (show 12 more authors) (2017) Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis. SCIENTIFIC REPORTS, 7.


O' Neill, Paul M, Stocks, Paul A, Sabbani, Sunil, Roberts, Natalie L, Amewu, Richard K, Shore, Emma R, Aljayyoussi, Ghaith, Angulo-Barturen, Inigo, Belen, Maria, Jimenez-Diaz,
et al (show 12 more authors) (2018) Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria. BIOORGANIC & MEDICINAL CHEMISTRY, 26 (11). 2996 - 3005.


Jiang, Zhengyun, Hong, W David, Cui, Xiping, Gao, Hongcan, Wu, Panpan, Chen, Yingshan, Shen, Ding, Yang, Yang, Zhang, Bingjie, Taylor, Mark J
et al (show 4 more authors) (2017) Synthesis and structure-activity relationship of N-4-benzylamine-N-2-isopropyl-quinazoline-2,4-diamines derivatives as potential antibacterial agents. RSC ADVANCES, 7 (82). 52227 - 52237.


Nixon, Gemma L, Pidathala, Chandrakala, Shone, Alison E, Antoine, Thomas, Fisher, Nicholas, O'Neill, Paul M ORCID: 0000-0003-4338-0317, Ward, Stephen A and Biagini, Giancarlo A
(2013) Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era. FUTURE MEDICINAL CHEMISTRY, 5 (13). 1573 - 1591.


Wu, Pan-Pan, He, Hao, Hong, W David, Wu, Tong-Rong, Huang, Gui-Ying, Zhong, Ying-Ying, Tu, Bo-Rong, Gao, Min, Zhou, Jun, Zhao, Su-Qing
et al (show 6 more authors) (2018) The biological evaluation of fusidic acid and its hydrogenation derivative as antimicrobial and anti-inflammatory agents. INFECTION AND DRUG RESISTANCE, 11. 1945 - 1957.


Yu, Pan, Yang, Jia-Ning, Yan, Jin-Wu, Meng, Zhi-Zhong, Hong, W David, Roberts, Adam P, Ward, Stephen A, Zhang, Lei and Li, Shan
(2020) A novel fluorescent probe for the detection of AmpC beta-lactamase and the application in screening beta-lactamase inhibitors. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 234.

This list was generated on Sat Apr 17 00:08:52 2021 BST.