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Number of items: 13.


Kamalian, Laleh, Douglas, Oisin, Jolly, Carol E, Snoeys, Jan, Simic, Damir, Monshouwer, Mario, Williams, Dominic P ORCID: 0000-0002-0758-3152, Park, B Kevin ORCID: 0000-0001-8384-824X and Chadwick, Amy E ORCID: 0000-0002-7399-8655
(2019) Acute Metabolic Switch Assay Using Glucose/Galactose Medium in HepaRG Cells to Detect Mitochondrial Toxicity. Current protocols in toxicology, 80 (01). e76-.


Bell, Catherine C, Dankers, Anita CA, Lauschke, Volker M, Sison-Young, Rowena, Jenkins, Roz, Rowe, Cliff, Goldring, Chris E, Park, Kevin ORCID: 0000-0001-8384-824X, Regan, Sophie L, Walker, Tracy
et al (show 12 more authors) (2018) Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study. TOXICOLOGICAL SCIENCES, 162 (2). pp. 655-666.


Richert, Lysiane, Baze, Audrey, Parmentier, Celine, Gerets, Helga HJ, Sison-Young, Rowena, Dorau, Martina, Lovatt, Cerys, Czich, Andreas, Goldring, Christopher, Park, B Kevin ORCID: 0000-0001-8384-824X
et al (show 3 more authors) (2016) Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats. TOXICOLOGY LETTERS, 258. pp. 207-215.


Lazic, Stanley E, Semenova, Elizaveta ORCID: 0000-0002-8271-2575 and Williams, Dominic P ORCID: 0000-0002-0758-3152
(2020) Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative organ weights. Scientific reports, 10 (1). 6625-.


Antoine, Daniel James, Williams, Dominic P, Kipar, Anja, Laverty, Hugh and Park, B Kevin ORCID: 0000-0001-8384-824X
(2020) Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity (Retraction of Vol 16, Pg 479, 2010). MOLECULAR MEDICINE, 26 (1). pp. 479-490.


Antoine, Daniel James, Williams, Dominic P ORCID: 0000-0002-0758-3152, Kipar, Anja ORCID: 0000-0001-7289-3459, Laverty, Hugh and Park, B Kevin ORCID: 0000-0001-8384-824X
(2020) Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatoxicity (Expression of Concern of Vol 16, Pg 479, 2010). MOLECULAR MEDICINE, 26 (1). 13-.


O'Brien, Katie A ORCID: 0000-0002-0189-1971, McNally, Ben D, Sowton, Alice P ORCID: 0000-0002-3718-7783, Murgia, Antonio, Armitage, James, Thomas, Luke W, Krause, Fynn N, Maddalena, Lucas A, Francis, Ian, Kavanagh, Stefan
et al (show 5 more authors) (2021) Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress. BMC biology, 19 (1). 265-.


Bell, Catherine C ORCID: 0000-0003-2548-3427, Chouhan, Bhavik, Andersson, Linda C, Andersson, Håkan, Dear, James W, Williams, Dominic P ORCID: 0000-0002-0758-3152 and Söderberg, Magnus
(2020) Functionality of primary hepatic non-parenchymal cells in a 3D spheroid model and contribution to acetaminophen hepatotoxicity. Archives of toxicology, 94 (4). pp. 1251-1263.


Leedale, Joseph ORCID: 0000-0001-9010-4126, Colley, Helen E, Gaskell, Harriet, Williams, Dominic P ORCID: 0000-0002-0758-3152, Bearon, Rachel N ORCID: 0000-0001-8461-0823, Chadwick, Amy E ORCID: 0000-0002-7399-8655, Murdoch, Craig ORCID: 0000-0003-0053-7468 and Webb, Steven D
(2019) In silico-guided optimisation of oxygen gradients in hepatic spheroids. Computational Toxicology, 12. p. 100093.


Weaver, Richard J, Blomme, Eric A, Chadwick, Amy E ORCID: 0000-0002-7399-8655, Copple, Ian M ORCID: 0000-0003-4101-1913, Gerets, Helga HJ, Goldring, Christopher E, Guillouzo, Andre, Hewitt, Philip G, Ingelman-Sundberg, Magnus, Jensen, Klaus Gjervig
et al (show 12 more authors) (2020) Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models. NATURE REVIEWS DRUG DISCOVERY, 19 (2). pp. 131-148.


Brecklinghaus, Tim, Albrecht, Wiebke, Kappenberg, Franziska, Duda, Julia, Vartak, Nachiket, Edlund, Karolina, Marchan, Rosemarie, Ghallab, Ahmed, Cadenas, Cristina, Günther, Georgia
et al (show 13 more authors) (2022) The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds. Chemico-Biological Interactions, 351. p. 109728.


Kamalian, Laleh, Douglas, Oisin, Jolly, Carol E, Snoeys, Jan, Simic, Damir, Monshouwer, Mario, Williams, Dominic P ORCID: 0000-0002-0758-3152, Park, B Kevin ORCID: 0000-0001-8384-824X and Chadwick, Amy E ORCID: 0000-0002-7399-8655
(2018) The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity. TOXICOLOGY IN VITRO, 53. pp. 136-147.


Jolly, Carol E, Douglas, Oisin, Kamalian, Laleh, Jenkins, Rosalind E, Beckett, Alison J ORCID: 0000-0001-8377-325X, Penman, Sophie L ORCID: 0000-0001-5326-1675, Williams, Dominic P ORCID: 0000-0002-0758-3152, Monshouwer, Mario, Simic, Damir, Snoeys, Jan
et al (show 2 more authors) (2020) The utility of a differentiated preclinical liver model, HepaRG cells, in investigating delayed toxicity via inhibition of mitochondrial-replication induced by fialuridine. Toxicology and applied pharmacology, 403. 115163-.

This list was generated on Sun Feb 11 08:11:34 2024 GMT.