 | Up a level |
Hughes, Juliette H 
ORCID: 0000-0001-6155-4136, Keenan, Craig M ORCID: 0000-0002-8782-8016, Sutherland, Hazel, Edwards, Henry R, Wilson, Peter JM, Ranganath, Lakshminarayan R, Jarvis, Jonathan C, Bou-Gharios, George and Gallagher, James A ORCID: 0000-0002-0852-279X
(2021)
Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces.
Calcified Tissue International, 108 (2).
pp. 207-218.
Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hickton, Bryony, Ross, Gordon A, Milan, Anna M ORCID: 0000-0002-0452-2338, Hughes, Andrew T, Wilson, Peter JM, Sutherland, Hazel, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Roberts, Norman B et al (show 3 more authors)
(2022)
Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria.
METABOLITES, 12 (10).
927-.
Hughes, Juliette H ORCID: 0000-0001-6155-4136, Liu, Ke, Plagge, Antonius ORCID: 0000-0001-6592-1343, Wilson, Peter JM, Sutherland, Hazel, Norman, Brendan P ORCID: 0000-0001-9293-4852, Hughes, Andrew T, Keenan, Craig M ORCID: 0000-0002-8782-8016, Milan, Anna M ORCID: 0000-0002-0452-2338, Sakai, Takao ORCID: 0000-0002-7375-5450 et al (show 3 more authors)
(2019)
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria.
Human Molecular Genetics, 28 (23).
pp. 3928-3939.
Hughes, Juliette H ORCID: 0000-0001-6155-4136, Liu, Ke, Plagge, Antonius ORCID: 0000-0001-6592-1343, Wilson, Peter JM, Sutherland, Hazel, Norman, Brendan P, Hughes, Andrew T, Keenan, Craig M, Milan, Anna M, Sakai, Takao ORCID: 0000-0002-7375-5450 et al (show 3 more authors)
(2019)
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria.
Human molecular genetics.
Hughes, Juliette H ORCID: 0000-0001-6155-4136, Wilson, Peter JM, Sutherland, Hazel, Judd, Shirley, Hughes, Andrew T, Milan, Anna M ORCID: 0000-0002-0452-2338, Jarvis, Jonathan C, Bou-Gharios, George, Ranganath, Lakshminarayan R and Gallagher, James A
(2020)
Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria.
JOURNAL OF INHERITED METABOLIC DISEASE, 43 (2).
pp. 259-268.
Wilson, Peter JM, Ranganath, Lakshminarayan R, Bou-Gharios, George, Gallagher, James A ORCID: 0000-0002-0852-279X and Hughes, Juliette H ORCID: 0000-0001-6155-4136
(2021)
Expression of tyrosine pathway enzymes in mice demonstrates that homogentisate 1,2-dioxygenase deficiency in the liver is responsible for homogentisic acid-derived ochronotic pigmentation.
JIMD reports, 58 (1).
pp. 52-60.
Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Sutherland, Hazel, Wilson, Peter JM, Berry, Neil G ORCID: 0000-0003-1928-0738, Hughes, Andrew T, Milan, Anna M, Jarvis, Jonathan C, Roberts, Norman B et al (show 3 more authors)
(2022)
Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism.
GENES & DISEASES, 9 (4).
pp. 1129-1142.
Pacheco-Pantoja, Elda Leonor, Dillon, Jane P ORCID: 0000-0002-7055-5664, Wilson, Peter JM, Fraser, William D and Gallagher, James A ORCID: 0000-0002-0852-279X
(2016)
c-Fos induction by gut hormones and extracellular ATP in osteoblastic-like cell lines.
Purinergic Signalling, 12 (4).
pp. 647-651.