Comparison between SELEX and single-step selection for the identification of bivalent aptamers for thrombin



Wilson, R, Bourne, C, Chaudhuri, R, Gregory, R, Kenny, J and Cossins, A
Comparison between SELEX and single-step selection for the identification of bivalent aptamers for thrombin. Angewandte Chemie International Edition. ISSN 1433-7851, 1521-3773 (Submitted)

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Abstract

The identification of bivalent aptamers for thrombin by SELEX and single-step selection are compared using next generation (massively parallel) sequencing and motif finding informatics. Results show that similar aptamers are identified by both methods.

Item Type: Article
Additional Information: 35 pages. Date: 2014 (submitted)
Subjects: Q Science > QP Physiology
Divisions: ?? sch_biomed ??
Depositing User: Symplectic Admin
Date Deposited: 06 Jan 2014 10:14
Last Modified: 17 Aug 2018 14:24
URI: https://livrepository.liverpool.ac.uk/id/eprint/14773

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