How does lorcaserin facilitate weight loss and who will benefit?



Roberts, Carl A ORCID: 0000-0003-4275-601X and Halford, Jason CG ORCID: 0000-0003-1629-3189
(2018) How does lorcaserin facilitate weight loss and who will benefit? NATURE REVIEWS ENDOCRINOLOGY, 14 (12). pp. 692-693.

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Abstract

Pharmacotherapy for obesity, as an adjunct to targeted behavioural modifications, can facilitate weight loss. Previous serotonergic candidates have been withdrawn owing to undesirable cardiovascular effects. A new study in a large sample of high-risk patients shows lorcaserin treatment leads to no greater increase in cardiovascular problems than placebo — what does this result mean for personalized pharmacotherapy for obesity?

Item Type: Article
Uncontrolled Keywords: Humans, Obesity, Weight Loss, Benzazepines, Overweight
Depositing User: Symplectic Admin
Date Deposited: 03 Jun 2019 13:33
Last Modified: 19 Jan 2023 00:42
DOI: 10.1038/s41574-018-0109-y
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3043674