Clinical outcomes following rhythm control for atrial fibrillation: is early better?



Kotalczyk, Agnieszka, Ding, Wern Yew ORCID: 0000-0003-3596-6545, Gupta, Dhiraj, Wright, David Justin and Lip, Gregory YH ORCID: 0000-0002-7566-1626
(2021) Clinical outcomes following rhythm control for atrial fibrillation: is early better? EXPERT REVIEW OF CARDIOVASCULAR THERAPY, 19 (4). pp. 277-287.

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Abstract

<b>Introduction</b>: An integral aspect of atrial fibrillation (AF) management involves better symptom control, incorporating a rate control, rhythm control, or a combination strategy. The 2020 ESC Guidelines suggest that rhythm control strategy should be recommended for symptomatic patients, to mitigate their symptoms and improve the quality of life. However, adequately powered randomized control trials and prospective 'real-world' registries are needed to fully assess the impact of early rhythm control strategies on clinical outcomes in patients with AF.<b>Objective</b>: In this narrative review, we discuss clinical outcomes following rhythm management approach among patients with AF, considering the effectiveness of an early intervention strategy.<b>Expert opinion</b>: Patients involvement and shared decision-making are crucial when deciding the optimal management strategy among patients with AF. For those with newly diagnosed symptomatic AF, an early invasive approach such as catheter ablation may have a role in preventing AF progression and subsequent pathophysiological changes.

Item Type: Article
Uncontrolled Keywords: Atrial fibrillation, cardioversion, catheter ablation, heart failure, rate control, rhythm control
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 11 May 2021 15:28
Last Modified: 18 Jan 2023 22:47
DOI: 10.1080/14779072.2021.1902307
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3122354