Adherence to the Atrial fibrillation Better Care pathway and the risk of adverse health outcomes in older care home residents with atrial fibrillation: a retrospective data linkage study 2003-18.


Ritchie, Leona A ORCID: 0000-0002-0392-1767, Harrison, Stephanie L ORCID: 0000-0002-8846-0946, Penson, Peter E ORCID: 0000-0001-6763-1489, Akbari, Ashley, Torabi, Fatemeh, Hollinghurst, Joe, Harris, Daniel, Oke, Oluwakayode B, Akpan, Asangaedem, Halcox, Julian P et al (show 3 more authors) (2024) Adherence to the Atrial fibrillation Better Care pathway and the risk of adverse health outcomes in older care home residents with atrial fibrillation: a retrospective data linkage study 2003-18. Age and ageing, 53 (2). afae021-.

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Abstract

<h4>Background</h4>The Atrial fibrillation Better Care (ABC) pathway is the gold-standard approach to atrial fibrillation (AF) management, but the effect of implementation on health outcomes in care home residents is unknown.<h4>Objective</h4>To examine associations between ABC pathway adherence and stroke, transient ischaemic attack, cardiovascular hospitalisation, major bleeding, mortality and a composite of all these outcomes in care home residents.<h4>Methods</h4>A retrospective cohort study of older care home residents (≥65 years) in Wales with AF was conducted between 1 January 2003 and 31 December 2018 using the Secure Anonymised Information Linkage Databank. Adherence to the ABC pathway was assessed at care home entry using pre-specified definitions. Cox proportional hazard and competing risk models were used to estimate the risk of health outcomes according to ABC adherence.<h4>Results</h4>From 14,493 residents (median [interquartile range] age 87.0 [82.6-91.2] years, 35.2% male) with AF, 5,531 (38.2%) were ABC pathway adherent. Pathway adherence was not significantly associated with risk of the composite outcome (adjusted hazard ratio, 95% confidence interval [CI]: 1.01 [0.97-1.05]). There was a significant independent association observed between ABC pathway adherence and a reduced risk of myocardial infarction (0.70 [0.50-0.98]), but a higher risk of haemorrhagic stroke (1.59 [1.06-2.39]). ABC pathway adherence was not significantly associated with any other individual health outcomes examined.<h4>Conclusion</h4>An ABC adherent approach in care home residents was not consistently associated with improved health outcomes. Findings should be interpreted with caution owing to difficulties in defining pathway adherence using routinely collected data and an individualised approach is recommended.

Item Type: Article
Uncontrolled Keywords: Humans, Atrial Fibrillation, Anticoagulants, Retrospective Studies, Information Storage and Retrieval, Aged, Aged, 80 and over, Critical Pathways, Female, Male, Outcome Assessment, Health Care
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 04 Jan 2024 16:25
Last Modified: 01 Mar 2024 09:55
DOI: 10.1093/ageing/afae021
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3177708
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