Lacrimal Sac Tumors--A Review.



Krishna, Y and Coupland, SE ORCID: 0000-0002-1464-2069
(2017) Lacrimal Sac Tumors--A Review. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.), 6 (2). 173 - 178.

[img] Text
Title page LS tumours_APJO_final.docx - Accepted Version

Download (26kB)
[img] Text
revised and final manuscript LS tumours_APJO_100317.docx - Accepted Version

Download (54kB)
[img] Image
Fig1.jpg - Accepted Version

Download (89kB)
[img] Image
Fig2.jpg - Accepted Version

Download (76kB)
[img] Image
Fig3.jpg - Accepted Version

Download (123kB)

Abstract

Tumors of the lacrimal sac are rare but their recognition and early management are imperative, as they are locally invasive and potentially life-threatening. Because of their rarity, large clinical studies with statistically significant data on the natural course, management, and prognosis of these neoplasms are unavailable. Current practices are therefore based on a few case series and a small number of isolated case reports. Most tumors are primary and of epithelial origin (60-94%), of which 55% are malignant. Lacrimal sac tumors typically present with epiphora and a palpable mass over the medial canthus and are thus often erroneously diagnosed as chronic dacryocystitis. A full history with clinical and diagnostic workup is essential to plan treatment, which is often multi-disciplinary. Statistically significant associations have been shown with higher tumor staging and size with increased metastatic risk and lower survival rates. Management usually involves complete surgical resection with adjuvant radiotherapy and/or chemotherapy for malignant lesions. Long-term follow-up is required, as recurrences and metastases can occur many years after initial treatment.

Item Type: Article
Depositing User: Symplectic Admin
Date Deposited: 09 Jun 2017 09:58
Last Modified: 14 Oct 2021 19:10
DOI: 10.22608/apo.201713
URI: https://livrepository.liverpool.ac.uk/id/eprint/3007892