A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens



Gallagher, AG ORCID: 0000-0003-2448-4145, Alorabi, JA, Wellings, DA, Lace, R ORCID: 0000-0001-9410-9506, Horsburgh, MJ ORCID: 0000-0002-3806-0039 and Williams, RL ORCID: 0000-0002-1954-0256
(2016) A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens. Advanced Healthcare Materials, 5 (16). 2013 - 2018.

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Abstract

A peptide hydrogel with an antimicrobial activity is developed as a bandage contact lens. The antimicrobial activity is enhanced with the addition of the biomolecules penicillin G or poly‐ε‐lysine and is positive against Staphylococcus aureus and Escherichia coli . The lens is also noncytotoxic toward a human corneal epithelial cell line and as a consequence is of great potential as a drug‐eluting bandage lens replacing conventional corneal ulcer treatment.

Item Type: Article
Uncontrolled Keywords: antimicrobial, bandage lens, cornea, drug delivery, hydrogel
Depositing User: Symplectic Admin
Date Deposited: 17 Aug 2018 14:26
Last Modified: 19 Nov 2021 11:53
DOI: 10.1002/adhm.201600258
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3025142

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