Impact of Lidocaine on Pain-Related Grooming in Cuttlefish

Kuo, Tzu-Hsin, Sneddon, Lynne U ORCID: 0000-0001-9787-3948, Spencer, Joseph W and Chiao, Chuan-Chin (2022) Impact of Lidocaine on Pain-Related Grooming in Cuttlefish. BIOLOGY-BASEL, 11 (11). 1560-.

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Abstract

Nociception is the neural process of encoding noxious stimuli and is typically accompanied by a reflex withdrawal response away from the potentially injurious stimulus. Studies on nociception in cephalopods have so far focused on octopus and squid, with no investigations to our knowledge on cuttlefish. Yet, these are an important species both in scientific and commercial use. Therefore, the present study demonstrated that a standard pain stimulus, acetic acid, induced grooming behaviour directed towards the injection site in cuttlefish and that the injection of lidocaine reduces grooming behaviours in acetic-acid-injected cuttlefish. Wound-directed behaviour demonstrates that the animal is aware of the damage; thus, when subjecting these animals to any painful treatments in the laboratory, researchers should consider alleviating pain by the administration of pain-relieving drugs.

Item Type:	Article
Uncontrolled Keywords:	cephalopoda, analgesia, acetic acid test, nociception
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Depositing User:	Symplectic Admin
Date Deposited:	24 Jan 2023 15:05
Last Modified:	24 Jan 2023 15:05
DOI:	10.3390/biology11111560
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3167861