Horne, Tanya, Orr, Victoria T and Hall, James PJ 
ORCID: 0000-0002-4896-4592
(2023)
How do interactions between mobile genetic elements affect horizontal gene transfer?
CURRENT OPINION IN MICROBIOLOGY, 73.
102282-.
Abstract
Horizontal gene transfer is central to bacterial adaptation and is facilitated by mobile genetic elements (MGEs). Increasingly, MGEs are being studied as agents with their own interests and adaptations, and the interactions MGEs have with one another are recognised as having a powerful effect on the flow of traits between microbes. Collaborations and conflicts between MGEs are nuanced and can both promote and inhibit the acquisition of new genetic material, shaping the maintenance of newly acquired genes and the dissemination of important adaptive traits through microbiomes. We review recent studies that shed light on this dynamic and oftentimes interlaced interplay, highlighting the importance of genome defence systems in mediating MGE-MGE conflicts, and outlining the consequences for evolutionary change, that resonate from the molecular to microbiome and ecosystem levels.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Bacteria, Gene Transfer, Horizontal, Interspersed Repetitive Sequences, Biological Evolution, Microbiota |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 06 Mar 2023 15:25 |
| Last Modified: | 10 Jun 2023 00:49 |
| DOI: | 10.1016/j.mib.2023.102282 |
| Open Access URL: | https://www.sciencedirect.com/science/article/pii/... |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3168798 |
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