A Hemilabile NHC-Gold Complex and its Application to the Redox Neutral 1,2-Oxyarylation of Feedstock Alkenes

Scott, Samuel C, Cadge, Jamie A, Boden, Grace K, Bower, John F ORCID: 0000-0002-7551-8221 and Russell, Christopher A (2023) A Hemilabile NHC-Gold Complex and its Application to the Redox Neutral 1,2-Oxyarylation of Feedstock Alkenes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 62 (23). e202301526-.

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Abstract

We describe a Au^I complex of a hemi-labile (C^N) N-heterocyclic carbene ligand that is able to mediate oxidative addition of aryl iodides. Detailed computational and experimental investigations have been undertaken to verify and rationalize the oxidative addition process. Application of this initiation mode has resulted in the first examples of "exogenous oxidant-free" Au^I /Au^III catalyzed 1,2-oxyarylations of ethylene and propylene. These demanding yet powerful processes establish these commodity chemicals as nucleophilic-electrophilic building blocks in catalytic reaction design.

Item Type:	Article
Uncontrolled Keywords:	Ethylene, Gold, NHC, Oxidative Addition, Oxyarylation
Divisions:	Faculty of Science and Engineering > School of Physical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	03 Apr 2023 15:53
Last Modified:	21 Sep 2023 09:04
DOI:	10.1002/anie.202301526
Open Access URL:	https://doi.org/10.1002/anie.202301526
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3169439