Diagnostic workup of childhood interstitial lung disease



Nathan, Nadia, Griese, Matthias, Michel, Katarzyna, Carlens, Julia, Gilbert, Carlee ORCID: 0000-0002-5340-5728, Emiralioglu, Nagehan, Torrent-Vernetta, Alba, Marczak, Honorata, Willemse, Brigitte, Delestrain, Celine
et al (show 1 more authors) (2023) Diagnostic workup of childhood interstitial lung disease. EUROPEAN RESPIRATORY REVIEW, 32 (167). 220188-.

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Abstract

Childhood interstitial lung diseases (chILDs) are rare and heterogeneous diseases with significant morbidity and mortality. An accurate and quick aetiological diagnosis may contribute to better management and personalised treatment. On behalf of the European Respiratory Society Clinical Research Collaboration for chILD (ERS CRC chILD-EU), this review summarises the roles of the general paediatrician, paediatric pulmonologists and expert centres in the complex diagnostic workup. Each patient's aetiological chILD diagnosis must be reached without prolonged delays in a stepwise approach from medical history, signs, symptoms, clinical tests and imaging, to advanced genetic analysis and specialised procedures including bronchoalveolar lavage and biopsy, if necessary. Finally, as medical progress is fast, the need to revisit a diagnosis of "undefined chILD" is stressed.

Item Type: Article
Uncontrolled Keywords: ERS CRC chILD-EU group, Lung, Humans, Lung Diseases, Interstitial, Diagnostic Imaging, Biopsy, Morbidity, Bronchoalveolar Lavage, Child
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Population Health
Depositing User: Symplectic Admin
Date Deposited: 25 Apr 2023 08:21
Last Modified: 04 May 2023 00:56
DOI: 10.1183/16000617.0188-2022
Open Access URL: https://doi.org/10.1183/16000617.0188-2022
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3169959