Patent foramen ovale: diagnostic evaluation and the role of device closure

Gonnah, Ahmed R, Bharadwaj, Mahima S, Nassar, Hassan, Abdelaziz, Hesham K and Roberts, David Hesketh ORCID: 0000-0001-6693-7523 (2022) Patent foramen ovale: diagnostic evaluation and the role of device closure. CLINICAL MEDICINE, 22 (5). pp. 441-448.

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Official URL: http://dx.doi.org/10.7861/clinmed.2022-0040

Abstract

Although seemingly benign, the presence of a patent foramen ovale (PFO) may play an important role in the pathophysiology of disease, specifically a paradoxical embolism leading to cryptogenic stroke. The European Society of Cardiology recently published guidelines detailing how PFOs are associated with paradoxical embolism and how they are diagnosed and managed. This review guides physicians in the diagnostic and referral process to a multidisciplinary team involved in PFO closure. It reviews the clinical trials comparing device closure with medical therapy and highlights the current NHS England commissioning process on PFO management. Finally, we give an overview of other conditions where PFO device closure may need to be considered.

Item Type:	Article
Uncontrolled Keywords:	patent foramen ovale, paradoxical embolism, cardiology, cryptogenic stroke, multidisciplinary team
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences > School of Medicine
Depositing User:	Symplectic Admin
Date Deposited:	16 May 2023 15:28
Last Modified:	14 Apr 2024 12:34
DOI:	10.7861/clinmed.2022-0040
Open Access URL:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC95950...
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3170406