Attaching protein-adsorbing silica particles to the surface of cotton substrates for bioaerosol capture including SARS-CoV-2



Collings, Kieran, Boisdon, Cedric, Sham, Tung-Ting ORCID: 0000-0002-9648-4964, Skinley, Kevin, Oh, Hyun-Kyung, Prince, Tessa ORCID: 0000-0002-8796-2629, Ahmed, Adham, Pennington, Shaun H, Brownridge, Philip J, Edwards, Thomas
et al (show 5 more authors) (2023) Attaching protein-adsorbing silica particles to the surface of cotton substrates for bioaerosol capture including SARS-CoV-2. Nature Communications, 14 (1). 5033-.

Access the full-text of this item by clicking on the Open Access link.

Abstract

<jats:title>Abstract</jats:title><jats:p>The novel coronavirus pandemic (COVID-19) has necessitated a global increase in the use of face masks to limit the airborne spread of the virus. The global demand for personal protective equipment has at times led to shortages of face masks for the public, therefore makeshift masks have become commonplace. The severe acute respiratory syndrome caused by coronavirus-2 (SARS-CoV-2) has a spherical particle size of ~97 nm. However, the airborne transmission of this virus requires the expulsion of droplets, typically ~0.6–500 µm in diameter (by coughing, sneezing, breathing, and talking). In this paper, we propose a face covering that has been designed to effectively capture SARS-CoV-2 whilst providing uncompromised comfort and breathability for the wearer. Herein, we describe a material approach that uses amorphous silica microspheres attached to cotton fibres to capture bioaerosols, including SARS CoV-2. This has been demonstrated for the capture of aerosolised proteins (cytochrome c, myoglobin, ubiquitin, bovine serum albumin) and aerosolised inactivated SARS CoV-2, showing average filtration efficiencies of ~93% with minimal impact on breathability.</jats:p>

Item Type: Article
Uncontrolled Keywords: Gossypium, Ubiquitin, Cotton Fiber, COVID-19, SARS-CoV-2
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Faculty of Science and Engineering > School of Electrical Engineering, Electronics and Computer Science
Depositing User: Symplectic Admin
Date Deposited: 21 Aug 2023 07:25
Last Modified: 18 Oct 2023 15:56
DOI: 10.1038/s41467-023-40696-x
Open Access URL: https://www.nature.com/articles/s41467-023-40696-x...
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3172251