Bernal, Johan F, Díaz, Paula L, Perez-Sepulveda, Blanca M, Valencia-Guerrero, María Fernanda, Clavijo, Viviana, Weisner, Magdalena, Montaño, Lucy Angeline, Arevalo, Stefany A, León, Ingrid Maribel, Castellanos, Luis Ricardo et al (show 6 more authors)
(2023)
A one health approach based on genomics for enhancing the Salmonella enterica surveillance in Colombia.
IJID Regions, 9.
pp. 80-87.
Abstract
<h4>Objectives</h4>This study aimed to provide evidence of the domestic benefits of introducing an integrative genomic analysis from the One Health approach in the national surveillance of <i>Salmonella enterica</i> between 1997-2017 in Colombia.<h4>Methods</h4>Data on <i>Salmonella</i> from clinical laboratory-based surveillance between 1997-2017 and from a national cross-sectional study at chicken retail stores in Colombia were compared using a phenotypic, molecular, and genomic approaches. Additional analysis by serovar using single nucleotide polymorphism was developed to increase the resolution of the relatedness between the interfaces.<h4>Results</h4>Locally, the diversity and pathogenic factors of the prevalent <i>S. enterica</i> serovars associated with foodborne disease in Colombia were described using laboratory, pulse field gel electrophoresis, and whole genome sequencing data. For example, the resolution of pulse field gel electrophoresis allowed the description of two main foodborne clusters of <i>Salmonella Enteritidis</i> isolates, which were expanded to eight foodborne clades using whole genome sequencing. Likewise, virulence factors and antimicrobial resistance determinants, and mobile genetic elements that converged in the foodborne clades should be considered a public health concern in Colombia. All results by serovar were compiled in an interactive easy to share report.<h4>Conclusion</h4>Whole genome sequencing is a technology that provides a precise assessment of emerging foodborne risks such as the <i>Salmonella</i> foodborne clades, but it requires an integrative and continued collaboration between the stakeholders across the One Health sectors to promote appropriated actions and policies in public health.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Antimicrobial resistance, Foodborne, One health, Salmonella, Virulence, WGS |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 16 Oct 2023 08:47 |
| Last Modified: | 08 Dec 2023 17:10 |
| DOI: | 10.1016/j.ijregi.2023.09.008 |
| Open Access URL: | https://www.sciencedirect.com/science/article/pii/... |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3173750 |
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