Effect of intrastromal corneal ring segments on in vivo corneal biomechanics in keratoconus: 1-year results.


Vinciguerra, Riccardo ORCID: 0000-0002-2280-9981, Fernández-Vega-Cueto, Luis ORCID: 0000-0001-9197-5847, Roberts, Cynthia J ORCID: 0000-0002-0483-4163, Poo-Lopez, Arancha, Eliasy, Ashkan ORCID: 0000-0002-4473-1900, Merayo-Lloves, Jesús ORCID: 0000-0003-3740-3754, Elsheikh, Ahmed ORCID: 0000-0001-7456-1749, Madrid-Costa, David ORCID: 0000-0003-3927-2858, Lisa, Carlos, Lisa, Carlos ORCID: 0000-0003-4600-427X et al (show 1 more authors) (2023) Effect of intrastromal corneal ring segments on in vivo corneal biomechanics in keratoconus: 1-year results. Journal of cataract and refractive surgery, 49 (12). pp. 1258-1263.

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Abstract

<h4>Purpose</h4>To evaluate the 1-year effects of the implantation of intrastromal corneal ring segments (ICRS) in keratoconus (KC) on the dynamic corneal response (DCR) parameters obtained with the Corvis.<h4>Setting</h4>Fernández-Vega Ophthalmological Institute, Oviedo, Spain.<h4>Design</h4>Prospective, single-center, clinical study.<h4>Methods</h4>Included were patients who underwent ICRS implantation for KC over a period of 1 year. On the day of the surgery and at least 6 months after ICRS implantation, the following measurements were made: corrected distance and uncorrected distance visual acuity, corneal tomography indices with the Pentacam, biomechanically corrected intraocular pressure and the Corvis DCRs (integrated inverse concave radius, deformation amplitude ratio, stiffness parameter at first applanation, stress-strain index [SSI] and the highest concavity radius).<h4>Results</h4>30 eyes were included with a mean follow-up time of 15 months. Statistical analysis showed that ICRS implantation induced significant improvements in corneal biomechanics measurements between preoperative and long-term follow-up as demonstrated by a significant increase in SSI (P = .003). To confirm that this difference was actually induced due to a stiffening between early postoperative (previously published) and long-term an additional t-test was done between month 1 and late follow-up which confirmed a significant stiffening in the value of SSI (P = .01).<h4>Conclusions</h4>Patients implanted with ICRS alone for KC showed a significantly stiffer response due to increased structural support compared with preoperative values and 1 month postoperative.

Item Type: Article
Uncontrolled Keywords: Cornea, Humans, Keratoconus, Prospective Studies, Academies and Institutes, Biomechanical Phenomena
Divisions: Faculty of Science and Engineering > School of Engineering
Depositing User: Symplectic Admin
Date Deposited: 20 Nov 2023 08:45
Last Modified: 02 Mar 2024 01:43
DOI: 10.1097/j.jcrs.0000000000001298
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3176891
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