Convenient syntheses of trans-resveratrol 3-O and 4′-O-β-<scp>d</scp>-glucuronides and a study of their aqueous stability

Fraser, Megan K, Gorecka, Aleksandra, Yates, Edwin A ORCID: 0000-0001-9365-5433, Iggo, Jonathan A ORCID: 0000-0001-8070-1226, Baj, Krzysztof and Stachulski, Andrew V (2023) Convenient syntheses of trans-resveratrol 3-O and 4′-O-β-<scp>d</scp>-glucuronides and a study of their aqueous stability. Organic Chemistry Frontiers.

Access the full-text of this item by clicking on the Open Access link.

Official URL: http://dx.doi.org/10.1039/d3qo01736b

Abstract

<jats:p>The monoglucuronides of resveratrol were prepared from resveratrol triacetate. They showed contrasting properties in aqueous solution: facile <jats:italic>E</jats:italic>/<jats:italic>Z</jats:italic> isomerisation for the 3-<jats:italic>O</jats:italic>-isomer and ready H/D exchange, without isomerisation, for the 4′-<jats:italic>O</jats:italic>-isomer.</jats:p>

Item Type:	Article
Uncontrolled Keywords:	Complementary and Integrative Health
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology Faculty of Science and Engineering > School of Physical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	19 Dec 2023 10:12
Last Modified:	15 Mar 2024 00:50
DOI:	10.1039/d3qo01736b
Open Access URL:	https://doi.org/10.1039/D3QO01736B
Related URLs:	Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3177517