`Cryo-EM': electron cryomicroscopy, cryo electron microscopy or something else?

Henderson, Richard ORCID: 0000-0003-1444-0528 and Hasnain, Samar ORCID: 0000-0002-2854-4718 (2023) `Cryo-EM': electron cryomicroscopy, cryo electron microscopy or something else? IUCrJ, 10 (Pt 5). pp. 519-520.

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Official URL: http://dx.doi.org/10.1107/s2052252523006759

Abstract

Structural biology continues to benefit from an expanding toolkit, which is helping to gain unprecedented insight into the assembly and organization of multi-protein machineries, enzyme mechanisms and ligand/inhibitor binding. During the last ten years, cryoEM has become widely available and has provided a major boost to structure determination of membrane proteins and large multi-protein complexes. Many of the structures have now been made available at resolutions around 2 Å, where fundamental questions regarding enzyme mechanisms can be addressed. Over the years, the abbreviation cryoEM has been understood to stand for different things. We wish the wider community to engage and clarify the definition of cryoEM so that the expanding literature involving cryoEM is unified.

Item Type:	Article
Uncontrolled Keywords:	Membrane Proteins, Cryoelectron Microscopy
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Depositing User:	Symplectic Admin
Date Deposited:	26 Mar 2024 10:01
Last Modified:	26 Mar 2024 15:29
DOI:	10.1107/s2052252523006759
Open Access URL:	https://doi.org/10.1107/S2052252523006759
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3179925