Adult brain tumour research in 2024: Status, challenges and recommendations.



Purshouse, Karin, Bulbeck, Helen J, Rooney, Alasdair G, Noble, Karen E, Carruthers, Ross D, Thompson, Gerard, Hamerlik, Petra, Yap, Christina, Kurian, Kathreena M, Jefferies, Sarah J
et al (show 4 more authors) (2024) Adult brain tumour research in 2024: Status, challenges and recommendations. Neuropathology and applied neurobiology, 50 (2). e12979-.

[img] PDF
2024-NAN-0026-RESUBMISSIONDv2_CLEAN.pdf - Author Accepted Manuscript

Download (825kB) | Preview

Abstract

In 2015, a groundswell of brain tumour patient, carer and charity activism compelled the UK Minister for Life Sciences to form a brain tumour research task and finish group. This resulted, in 2018, with the UK government pledging £20m of funding, to be paralleled with £25m from Cancer Research UK, specifically for neuro-oncology research over the subsequent 5 years. Herein, we review if and how the adult brain tumour research landscape in the United Kingdom has changed over that time and what challenges and bottlenecks remain. We have identified seven universal brain tumour research priorities and three cross-cutting themes, which span the research spectrum from bench to bedside and back again. We discuss the status, challenges and recommendations for each one, specific to the United Kingdom.

Item Type: Article
Uncontrolled Keywords: Humans, Brain Neoplasms, Biomedical Research, Adult, United Kingdom
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Depositing User: Symplectic Admin
Date Deposited: 15 Apr 2024 10:00
Last Modified: 27 Apr 2024 02:20
DOI: 10.1111/nan.12979
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3180332