Browse by People

Up a level
Export as [feed] RSS [feed] RSS 2.0 Short Author List
Number of items: 11.


Soares, Pedro, Gadd, Morgan S, Frost, Julianty ORCID: 0000-0001-8209-2575, Galdeano, Carles, Ellis, Lucy, Epemolu, Ola, Rocha, Sonia, Read, Kevin D and Ciulli, Alessio (2018) Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2<i>S</i>,4<i>R</i>)-1-((<i>S</i>)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyI)-4-hydroxy-<i>N</i>-(4-(4-methylthiazol-5-yl)benzyppyrrolidine-2-carboxamide (VH298). JOURNAL OF MEDICINAL CHEMISTRY, 61 (2). pp. 599-618.


Batie, Michael ORCID: 0000-0002-7508-6641, Frost, Julianty ORCID: 0000-0001-8209-2575, Frost, Mark ORCID: 0000-0001-7209-2897, Wilson, James W ORCID: 0000-0002-9373-6919, Schofield, Pieta ORCID: 0000-0002-6398-2537 and Rocha, Sonia (2019) Hypoxia Induces Rapid Changes to Histone Methylation and Reprograms Chromatin. Science, 363 (6432). pp. 1222-1226.


Batie, Michael, Frost, Julianty, Frost, Mark, Wilson, James, Schofield, Pieta ORCID: 0000-0002-6398-2537 and Rocha, Sonia ORCID: 0000-0002-2413-4981 (2019) Hypoxia induces rapid changes to histone methylation reprogramming chromatin for the cellular response: Supplementary material. bioRxiv. p. 513069.


Frost, Julianty ORCID: 0000-0001-8209-2575, Galdeano, Carles, Soares, Pedro, Gadd, Morgan S, Grzes, Katarzyna M, Ellis, Lucy, Epemolu, Ola, Shimamura, Satoko, Bantscheff, Marcus, Grandi, Paola et al (show 4 more authors) (2016) Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition. Nature communications, 7 (1).


Frost, Julianty ORCID: 0000-0001-8209-2575, Ciulli, Alessio ORCID: 0000-0002-8654-1670 and Rocha, Sonia ORCID: 0000-0002-2413-4981 (2019) RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response. Wellcome open research, 4. 17-.


Batie, Michael ORCID: 0000-0002-7508-6641, Frost, Julianty ORCID: 0000-0001-8209-2575, Shakir, Dilem and Rocha, Sonia (2022) Regulation of chromatin accessibility by hypoxia and HIF. BIOCHEMICAL JOURNAL, 479 (6). pp. 767-786.


Batie, Michael, Frost, Julianty, Shakir, Dilem and Rocha, Sonia ORCID: 0000-0002-2413-4981 (2022) Regulation of chromatin accessibility by hypoxia and HIF. The Biochemical journal, 479 (6). 767 - 786.


Frost, Julianty, Frost, Mark, Batie, Michael, Jiang, Hao ORCID: 0000-0003-4123-4930 and Rocha, Sonia ORCID: 0000-0002-2413-4981 (2020) Roles Of HIF and 2-Oxoglutarate Dependent Enzymes in Controlling Gene Expression In Hypoxia. Cancers.


Frost, Julianty ORCID: 0000-0001-8209-2575, Frost, Mark ORCID: 0000-0001-7209-2897, Batie, Michael ORCID: 0000-0002-7508-6641, Jiang, Hao and Rocha, Sonia (2021) Roles of HIF and 2-Oxoglutarate-Dependent Dioxygenases in Controlling Gene Expression in Hypoxia. CANCERS, 13 (2). 350-.


Frost, Julianty ORCID: 0000-0001-8209-2575, Rocha, Sonia ORCID: 0000-0002-2413-4981 and Ciulli, Alessio ORCID: 0000-0002-8654-1670 (2021) VHL ligand binding increases intracellular level of VHL. Journal of Biological Chemistry, 297 (2). 2021.04.12.439487-.


Frost, Julianty ORCID: 0000-0001-8209-2575, Rocha, Sonia and Ciulli, Alessio (2021) Von Hippel-Lindau (VHL) small-molecule inhibitor binding increases stability and intracellular levels of VHL protein. JOURNAL OF BIOLOGICAL CHEMISTRY, 297 (2). 100910-.

This list was generated on Sun Mar 24 19:33:46 2024 GMT.