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Hong, W David, Benayoud, Farid, Nixon, Gemma L, Ford, Louise, Johnston, Kelly L, Clare, Rachel H, Cassidy, Andrew, Cook, Darren AN, Siu, Amy, Shiotani, Motohiro et al (show 24 more authors)
(2019)
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116 (4).
pp. 1414-1419.
Johnston, Kelly L, Hong, W David, Turner, Joseph D, O'Neill, Paul M ORCID: 0000-0003-4338-0317, Ward, Stephen A and Taylor, Mark J
(2021)
Anti-Wolbachia drugs for filariasis.
TRENDS IN PARASITOLOGY, 37 (12).
pp. 1068-1081.
Fernandez-Alvaro, Elena, Hong, W David, Nixon, Gemma L, O'Neil, Paul M and Calderon, Felix
(2016)
Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action.
JOURNAL OF MEDICINAL CHEMISTRY, 59 (12).
pp. 5587-5603.
McGillan, Paul, Berry, Neil G ORCID: 0000-0003-1928-0738, Nixon, Gemma L, Leung, Suet C, Webborn, Peter JH, Wenlock, Mark C, Kavanagh, Stefan, Cassidy, Andrew, Clare, Rachel H, Cook, Darren A et al (show 6 more authors)
(2021)
Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis.
ACS Medicinal Chemistry Letters, 12 (9).
pp. 1421-1426.
Johnston, Kelly L, Cook, Darren AN, Berry, Neil G ORCID: 0000-0003-1928-0738, Hong, W David, Clare, Rachel H, Goddard, Megan, Ford, Louise, Nixon, Gemma L, O'Neill, Paul M ORCID: 0000-0003-4338-0317, Ward, Stephen A et al (show 1 more authors)
(2017)
Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library.
SCIENCE ADVANCES, 3 (09).
eaao1551-.
Jeffreys, Laura N, Ardrey, Alison, Hafiz, Taghreed A, Dyer, Lauri-Anne, Warman, Ashley J, Mosallam, Nada, Nixon, Gemma L, Fisher, Nicholas E, Hong, W David, Leung, Suet C et al (show 11 more authors)
(2023)
Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis.
ACS INFECTIOUS DISEASES, 9 (2).
pp. 221-238.
Clare, Rachel H, Bardelle, Catherine, Harper, Paul, Hong, W David, Borjesson, Ulf, Johnston, Kelly L, Collier, Matthew, Myhill, Laura, Cassidy, Andrew, Plant, Darren et al (show 21 more authors)
(2019)
Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides.
NATURE COMMUNICATIONS, 10 (1).
11-.
Jiang, Zhengyun, Hong, W David, Cui, Xiping, Gao, Hongcan, Wu, Panpan, Chen, Yingshan, Shen, Ding, Yang, Yang, Zhang, Bingjie, Taylor, Mark J et al (show 4 more authors)
(2017)
Synthesis and structure-activity relationship of N-4-benzylamine-N-2-isopropyl-quinazoline-2,4-diamines derivatives as potential antibacterial agents.
RSC ADVANCES, 7 (82).
pp. 52227-52237.
Amporndanai, Kangsa, Pinthong, Nattapon ORCID: 0000-0002-0740-9496, O'Neill, Paul M, Hong, W David, Amewu, Richard K ORCID: 0000-0002-4676-436X, Pidathala, Chandrakala, Berry, Neil G ORCID: 0000-0003-1928-0738, Leung, Suet C, Ward, Stephen A, Biagini, Giancarlo A et al (show 2 more authors)
(2022)
Targeting the Ubiquinol-Reduction (Q(i)) Site of the Mitochondrial Cytochrome bc(1) Complex for the Development of Next Generation Quinolone Antimalarials.
BIOLOGY-BASEL, 11 (8).
1109-.
Hong, W David, O'Neill, Paul M ORCID: 0000-0003-4338-0317, Taylor, Mark J, Turner, Joseph D, Ward, Stephen A, Gusovsky, Fabian, Benayoud, Farid, Shibuguchi, Nao, Girish, Dixit, Fang, Francis Gerard et al (show 9 more authors)
(2023)
Transformation of the Manufacturing Process from Discovery to Kilogram Scale for AWZ1066S: A Highly Specific Anti-Wolbachia Drug Candidate for a Short-Course Treatment of Filariasis.
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 27 (1).
pp. 42-53.
Wu, Pan-Pan, He, Hao, Hong, W David, Wu, Tong-Rong, Huang, Gui-Ying, Zhong, Ying-Ying, Tu, Bo-Rong, Gao, Min, Zhou, Jun, Zhao, Su-Qing et al (show 6 more authors)
(2018)
The biological evaluation of fusidic acid and its hydrogenation derivative as antimicrobial and anti-inflammatory agents.
INFECTION AND DRUG RESISTANCE, 11.
pp. 1945-1957.
Yu, Pan, Yang, Jia-Ning, Yan, Jin-Wu, Meng, Zhi-Zhong, Hong, W David, Roberts, Adam P, Ward, Stephen A, Zhang, Lei and Li, Shan
(2020)
A novel fluorescent probe for the detection of AmpC beta-lactamase and the application in screening beta-lactamase inhibitors.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 234.
118257-.