 | Up a level |
Viggars, Mark R, Sutherland, Hazel, Lanmueller, Hermann, Schmoll, Martin, Bijak, Manfred and Jarvis, Jonathan C
(2023)
Adaptation of the transcriptional response to resistance exercise over 4 weeks of daily training.
FASEB JOURNAL, 37 (1).
e22686-.
Hughes, Juliette H 
ORCID: 0000-0001-6155-4136, Keenan, Craig M ORCID: 0000-0002-8782-8016, Sutherland, Hazel, Edwards, Henry R, Wilson, Peter JM, Ranganath, Lakshminarayan R, Jarvis, Jonathan C, Bou-Gharios, George and Gallagher, James A ORCID: 0000-0002-0852-279X
(2021)
Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces.
Calcified Tissue International, 108 (2).
pp. 207-218.
Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hickton, Bryony, Ross, Gordon A, Milan, Anna M ORCID: 0000-0002-0452-2338, Hughes, Andrew T, Wilson, Peter JM, Sutherland, Hazel, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Roberts, Norman B et al (show 3 more authors)
(2022)
Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria.
METABOLITES, 12 (10).
927-.
Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Ross, Gordon A, Milan, Anna M ORCID: 0000-0002-0452-2338, Hughes, Andrew T, Sutherland, Hazel, Jarvis, Jonathan C, Roberts, Norman B, Gallagher, James A ORCID: 0000-0002-0852-279X and Ranganath, Lakshminarayan R
(2019)
A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria.
Clinical chemistry, 65 (4).
pp. 530-539.
Keenan, Craig M ORCID: 0000-0002-8782-8016, Beckett, Alison J ORCID: 0000-0001-8377-325X, Sutherland, Hazel, Ranganath, Lakshminarayan R, Jarvis, Jonathan C, Prior, Ian A ORCID: 0000-0002-4055-5161 and Gallagher, James A
(2019)
Concentric lamellae - novel microanatomical structures in the articular calcified cartilage of mice.
SCIENTIFIC REPORTS, 9 (1).
11188-.
Hughes, Juliette H ORCID: 0000-0001-6155-4136, Liu, Ke, Plagge, Antonius ORCID: 0000-0001-6592-1343, Wilson, Peter JM, Sutherland, Hazel, Norman, Brendan P ORCID: 0000-0001-9293-4852, Hughes, Andrew T, Keenan, Craig M ORCID: 0000-0002-8782-8016, Milan, Anna M ORCID: 0000-0002-0452-2338, Sakai, Takao ORCID: 0000-0002-7375-5450 et al (show 3 more authors)
(2019)
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria.
Human Molecular Genetics, 28 (23).
pp. 3928-3939.
Hughes, Juliette H ORCID: 0000-0001-6155-4136, Liu, Ke, Plagge, Antonius ORCID: 0000-0001-6592-1343, Wilson, Peter JM, Sutherland, Hazel, Norman, Brendan P, Hughes, Andrew T, Keenan, Craig M, Milan, Anna M, Sakai, Takao ORCID: 0000-0002-7375-5450 et al (show 3 more authors)
(2019)
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria.
Human molecular genetics.
Sutherland, Hazel, Conley, Michaela J, Emmott, Edward ORCID: 0000-0002-3239-8178, Streetley, James, Goodfellow, Ian G and Bhella, David
(2021)
The Cryo-EM Structure of Vesivirus 2117 Highlights Functional Variations in Entry Pathways for Viruses in Different Clades of the Vesivirus Genus.
JOURNAL OF VIROLOGY, 95 (13).
e0028221-.
Hughes, Juliette H ORCID: 0000-0001-6155-4136, Wilson, Peter JM, Sutherland, Hazel, Judd, Shirley, Hughes, Andrew T, Milan, Anna M ORCID: 0000-0002-0452-2338, Jarvis, Jonathan C, Bou-Gharios, George, Ranganath, Lakshminarayan R and Gallagher, James A
(2020)
Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria.
JOURNAL OF INHERITED METABOLIC DISEASE, 43 (2).
pp. 259-268.
Davison, Andrew S ORCID: 0000-0001-5501-4475, Norman, Brendan P ORCID: 0000-0001-9293-4852, Sutherland, Hazel, Milan, Anna M, Gallagher, James A ORCID: 0000-0002-0852-279X, Jarvis, Jonathan C and Ranganath, Lakshminarayan R
(2022)
Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria.
METABOLITES, 12 (6).
477-.
Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Sutherland, Hazel, Wilson, Peter JM, Berry, Neil G ORCID: 0000-0003-1928-0738, Hughes, Andrew T, Milan, Anna M, Jarvis, Jonathan C, Roberts, Norman B et al (show 3 more authors)
(2022)
Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism.
GENES & DISEASES, 9 (4).
pp. 1129-1142.
Khedr, Milad ORCID: 0000-0002-4998-2397, Cooper, Maggie S, Hughes, Andrew T, Milan, Anna M ORCID: 0000-0002-0452-2338, Davison, Andrew S ORCID: 0000-0001-5501-4475, Norman, Brendan P ORCID: 0000-0001-9293-4852, Sutherland, Hazel, Jarvis, Jonathan C, Fitzgerald, Richard, Markinson, Louise et al (show 5 more authors)
(2020)
Nitisinone causes acquired tyrosinosis in alkaptonuria.
JOURNAL OF INHERITED METABOLIC DISEASE, 43 (5).
pp. 1014-1023.
Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Sutherland, Hazel, Wilson, Peter J, Berry, Neil G, Hughes, Andrew T, Milan, Anna M, Jarvis, Jonathan C, Roberts, Norman B et al (show 3 more authors)
(2020)
Studies in alkaptonuria reveal new roles beyond drug clearance for phase I and II biotransformations in tyrosine metabolism.
biorxiv.
(Unpublished)
Hughes, Juliette H ORCID: 0000-0001-6155-4136, Keenan, Craig M ORCID: 0000-0002-8782-8016, Sutherland, Hazel, Edwards, Henry R, Ranganath, Lakshminarayan R, Bou-Gharios, George and Gallagher, James A ORCID: 0000-0002-0852-279X
(2021)
The anatomical distribution of ochronotic pigment in alkaptonuric mice reveals that ageing and mechanical loading make collagen susceptible to chemical attack.
.