Validation of the IBD-Control Questionnaire across different sociodemographic and clinical subgroups: Secondary analysis of a nationwide electronic survey

Gebeyehu, G, Taylor, Frederick ORCID: 0000-0002-1922-2354, Dobson, E, Cummings, F, Bloom, S, Kennedy, N, Christiansen, P and Bodger, Keith ORCID: 0000-0002-1825-3239 (2023) Validation of the IBD-Control Questionnaire across different sociodemographic and clinical subgroups: Secondary analysis of a nationwide electronic survey. Journal of Crohn's and Colitis, 18 (2). pp. 275-285.

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Official URL: http://dx.doi.org/10.1093/ecco-jcc/jjad147

Abstract

<h4>Background</h4>The IBD-Control Questionnaire is a simple, generic measure of patient-perceived disease control used increasingly in clinical practice and research. We aimed to address knowledge gaps in its psychometric performance, to ensure that it can be used with confidence in a variety of contexts.<h4>Methods</h4>We analysed 7341 responses to the IBD Registry COVID-19 survey, sent to 40 911 patients who completed an online self-assessment tool during the pandemic. Questions covered demographics, comorbidities, inflammatory bowel disease [IBD] sub-type, and IBD-Control Questionnaire and symptom scores [CD-PRO2 or UC-PRO2]. Psychometric properties of IBD-Control-8 were tested overall and within subgroups (Crohn's disease [CD], ulcerative colitis [UC] and IBD unclassified; male and female; ≤65 and >65 years; number of co-morbidities; deprivation status).<h4>Results</h4>Internal consistency was very strong overall [α: 0.84, ω: 0.89] and for each subgroup [α range: 0.81-0.85; ω: 0.86-0.90]. Construct validity was demonstrated by moderate correlation of each item with global rating [VAS] [rs range: 0.47-0.65], strong correlation between IBD-Control-8 score and VAS [rs = 0.74], moderate-to-strong with PRO2 scores [CD: rs = -0.718; UC: rs = -0.602] and significantly higher IBD-Control-8 scores for PRO2-remission vs PRO2-active, consistent across subgroups. Exploratory and confirmatory factor analyses demonstrated a two-factor model (items loading onto 'Health-related Quality of Life' [HRQoL] or 'Treatment' domains). Extensive tests for factorial invariance confirmed consistency.<h4>Conclusions</h4>IBD-Control-8 is a psychometrically robust scale which can be used across a range of populations. It offers a quick, reliable, and valid method of assessing patient-perceived control. The construct of 'control' includes traditional HRQoL and a novel domain relating to treatment perception.

Item Type:	Article
Uncontrolled Keywords:	Inflammatory bowel disease, patient-reported outcome measures
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Population Health
Depositing User:	Symplectic Admin
Date Deposited:	23 Aug 2023 08:04
Last Modified:	01 Mar 2024 13:04
DOI:	10.1093/ecco-jcc/jjad147
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3172300